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Regulation of Cerebellar Development and Tumorigenesis by CXCR4 and by Aurora and Polo-Like Kinases
During development, the precise regulation of the processes of proliferation, migration, and differentiation is required to establish proper organ structure and function and to prevent the deregulation that can lead to disease, ...
Regulation of Wee1 by PRMT5 in Brain Tumors
The eukaryotic cell cycle is characterized by a series of tightly orchestrated events during which cellular components are replicated and subsequently divided. In mammalian cells, the precise spatiotemporal control of cell ...
Extracellular Signal-Regulated Kinase as an Integrative Synapse-to-Nucleus Signal
The late phase of long-term synaptic potentiation (LTP) at glutamatergic synapses, which is thought to underlie the long lasting memory (at least hours), requires gene transcription in the nucleus. However, it remains elusive ...