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The role of TRIM39 in cell cycle and apoptosis
Within individual cells, the opposing processes of proliferation and apoptosis are precisely regulated. When this regulatory balance is interrupted, cells may become abnormal or even transformed. Understanding how to reverse ...
Role of Thioredoxin-Interacting Protein (TXNIP) in Regulating Redox Balance and Mitochondrial Function in Skeletal Muscle
The Muoio lab studies the interplay between lipid whole body energy balance,mitochondrial function and insulin action in skeletal muscle. Data from our lab suggests that lipid-induced insulin resistance in skeletal muscle ...