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The Role of the Stroma and CYR61 in Chemoresistance in Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer in part due to inherent resistance to chemotherapy, including the first-line drug gemcitabine. Gemcitabine is a nucleoside pyrimidine analog that has long been ...
The Role of Acetylation in the Metabolic Reprogramming of Cancer Cells
Identifying metabolic vulnerabilities of cancer cells remains a subject of investigation for the identification of potential metabolically based therapies for cancer. It is well known that proliferating cells become largely ...