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Generation of Functional Hepatocyte-Like Cells (HLCs) from Human Adipose-Derived Stem Cells (ADSCs) in 2D and 3D
(2019)
Mortality and morbidity rates caused by acute liver failure (ALF), acute-on-chronic
liver failure (ACLF) and chronic liver disease continue to rise because of drug induced
failure or viral hepatitis, currently with 2,000 ...
Design, Fabrication, and Implementation of Voxel-Based 3D Printed Heterogeneous Lung Lesion Phantoms for Assessment of CT Imaging Conditions on Texture Quantification
(2016)
Realistic virtual lesion models are valuable in medical imaging applications including
phantom design and observer studies. Radiologic diagnostic information rarely include
lesion texture due to the fact that texture ...
Evaluation of a Low Cost, Downstream Purification Process for Griffithsin - a Potential Broad Spectrum Viral Entry Inhibitor Produced in Engineered E. coli
(2017)
HIV infections remain a major public health issue with no current cure: in 2015, the
disease led to the deaths of 1.1 million people [1]. A viable preventative is Griffithsin
(GRFT), a lectin that binds and neutralizes the ...
Non-Invasive Characterization of Cartilage Properties Using MR Imaging
(2015)
Osteoarthritis (OA) is a degenerative disease affecting articular cartilage, leading
to loss of its structure and function. Early stage OA is characterized by changes
in the extracellular matrix (ECM), including a reduction ...
Influence of Outlet Boundary Conditions on Cerebrovascular Aneurysm Hemodynamics
(2016)
Computational fluid dynamic (CFD) studies of blood flow in cerebrovascular aneurysms
have potential to improve patient treatment planning by enabling clinicians and engineers
to model patient-specific geometries and compute ...
Automatic Volumetric Analysis of the Left Ventricle in 3D Apical Echocardiographs
(2015)
Apically-acquired 3D echocardiographs (echoes) are becoming a standard data component
in the clinical evaluation of left ventricular (LV) function. Ejection fraction (EF)
is one of the key quantitative biomarkers derived ...
The Effect of Thickness and Continuity of Motorcycle Helmet Shells on Performance
(2018)
Road accidents are the leading cause of death within the 15-29 years age range worldwide
and the risk of death for motorcyclists is 20 times that of car occupants. As such,
31% of over 10,250 annual road traffic deaths in ...
Design, Evaluation and Implementation of a Novel BME Instrumentation course at Makerere University, Kampala, Uganda
(2017)
Uganda is increasingly dependent upon imported biomedical pieces of equipment to support
patient care and health related research. Most of this equipment arrives without the
accompanying documentation, maintenance and support. ...
Effects of Statin-Induced Myopathy in a Human Skeletal Microphysiological System
(2018)
Advances in tissue engineering have led to the development of 3D biomimetic models
of human skeletal muscle (myobundles), which have a wide range of applications in
regenerative medicine, predictive drug testing and toxicology ...
Optimization of Conditions for Endothelial Seeding of Microfluidic Devices with Long Branching Networks and Small Channel Dimensions
(2013)
Many hematologic diseases may have interactions with proteins and endothelium within
small microvascular environments that are currently hard to understand. These effects
are hard to produce in vitro, and relevant studies ...