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Dosimetric and radiobiological fitting of xerostomia and dysphagia 12 months after treatment for head and neck tumors
(2018)
Oropharyngeal Squamous Cell Carcinoma (OPSCC) is by far the most predominant form
of head and neck cancer in the United States. The survival rate for OPSCC is very
high, which, while fortunate, yields many patients who are ...
Enhancing and Validating Modern Radiosurgery for Intracranial Metastases
(2018)
The recently-developed single-isocenter multi-target volumetric modulated arc therapy
(VMAT) provides several clinical benefits including significantly decreased treatment
time and cost-effectiveness compared to other traditional ...
Brachytherapy Dosimetry: Working towards in-vivo and end-to-end diametric checks in modern HDR brachytherapy
(2018)
Treatment errors can occur in high dose rate (HDR) brachytherapy, but, currently,
there is a lack of real-time treatment verification systems that are clinically available
and thus many errors are only determined retrospectively, ...
Development and Implementation of Intensity Modulated Radiation Therapy for Small Animal Irradiator
(2018)
Translational cancer research has been around for many years and has resultedin many
advancements in cancer treatment. Preclinical radiation therapy is an importanttool
used in some studies to better understand the biological ...
The development, characterization, and clinical investigation of a novel reusable radiochromic sheet for 2D dose measurement
(2019)
Purpose: Radiochromic film remains a useful and versatile clinical dosimetry tool.
While simple to use, current film options are single use, with no forms of reusable
film available commercially. Here we introduce a novel ...
Techniques to Improve Gynecological High-Dose-Rate Brachytherapy Treatments
(2019)
The thesis has two parts. The first project relates to real time dosimetry in Gynecological
(GYN) High Dose Rate (HDR) Brachytherapy Treatments and the second part investigates
a new workflow for Image Guided Brachytherapy ...
Comparison of planning techniques for single-isocenter multiple-target (SIMT) stereotactic radiosurgery
(2019)
Since 2010, Duke University Medical Center has used the single-isocenter technique
to treat patients with multiple brain metastases. The purpose of this project is to
compare treatment planning techniques for these patients ...
Validation of Isodose Curves for AIRO Mobile CT, P-32 Pure-Beta and I-131 Mixed Beta/Gamma Detection Utilizing Nano-Fiber Optic Detector
(2019)
Project 1: Validation of Isodose Curves for AIRO Mobile CT Purpose: Validate isodose
curves provided by the manufacturer for the Airo Mobile CT to determine if, indeed,
it is safe for those who are operating the machine. ...
Validation of Algorithmic CT Image Quality Metrics with Preferences of Radiologists
(2019)
Automated assessment of perceptual image quality on clinical Computed Tomography (CT)
data by computer algorithms has the potential to greatly facilitate data-driven monitoring
and optimization of CT image acquisition protocols. ...
Radiogenomics for Radiation Treatment Assessment of Advanced Lung Cancers
(2019)
Background: Radiomics describes the study of converting medical images into high-dimensional
quantitative features and following analysis for further decision making and genomics
focuses on the understanding genomes of individual ...