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Generation of Functional Hepatocyte-Like Cells (HLCs) from Human Adipose-Derived Stem Cells (ADSCs) in 2D and 3D 

Arinda, Beryl Ngabirano (2019)
Mortality and morbidity rates caused by acute liver failure (ALF), acute-on-chronic liver failure (ACLF) and chronic liver disease continue to rise because of drug induced failure or viral hepatitis, currently with 2,000 ...
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Design, Fabrication, and Implementation of Voxel-Based 3D Printed Heterogeneous Lung Lesion Phantoms for Assessment of CT Imaging Conditions on Texture Quantification 

Zheng, Yuese (2016)
Realistic virtual lesion models are valuable in medical imaging applications including phantom design and observer studies. Radiologic diagnostic information rarely include lesion texture due to the fact that texture ...
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A Tissue-Engineered Microvascular System to Evaluate Vascular Progenitor Cells for Angiogenic Therapies 

Brown Peters, Erica Cho (2015)
The ability of tissue engineered constructs to replace diseased or damaged organs is limited without the incorporation of a functional vascular system. To design microvasculature that recapitulates the vascular niche functions ...
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Micro-Anatomical Quantitative Imaging Towards Enabling Automated Diagnosis of Thick Tissues at the Point of Care 

Mueller, Jenna Lynne Hook (2015)
Histopathology is the clinical standard for tissue diagnosis. However, histopathology has several limitations including that it requires tissue processing, which can take 30 minutes or more, and requires a highly trained ...
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Evaluation of a Low Cost, Downstream Purification Process for Griffithsin - a Potential Broad Spectrum Viral Entry Inhibitor Produced in Engineered E. coli 

Oh, Leighanne (2017)
HIV infections remain a major public health issue with no current cure: in 2015, the disease led to the deaths of 1.1 million people [1]. A viable preventative is Griffithsin (GRFT), a lectin that binds and neutralizes the ...
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Peptide-Based Stimuli-Responsive Materials for Bioanalytical Applications 

Li, Linying (2017)
Surfaces with switchable properties in response to external stimuli (e.g., temperature and pH) have attracted substantial research interest because of their ability to modulate biomolecule activity, protein immobilization, ...
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Microfluidics-generated Double Emulsion Platform for High-Throughput Screening and Multicellular Spheroid Production with Controllable Microenvironment 

Chan, Hon Fai (2015)
High-throughput processing technologies hold critical position in biomedical research. These include screening of cellular response based on phenotypic difference and production of homogeneous chemicals and biologicals for ...
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Optimized approach to decision fusion of heterogeneous data for breast cancer diagnosis. 

Jesneck, JL; Nolte, LW; Baker, JA; Floyd, CE; Lo, JY (Med Phys, 2006-08)
As more diagnostic testing options become available to physicians, it becomes more difficult to combine various types of medical information together in order to optimize the overall diagnosis. To improve diagnostic performance, ...
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Non-uniform Interstitial Loading in Cardiac Microstructure During Impulse Propagation 

Roberts, Sarah F. (2009)
Impulse propagation in cardiac muscle is determined not only by the excitable properties of the myocyte membrane, but also by the gross and fine structure of cardiac muscle. Ionic diffusion pathways are defined by the muscle's ...
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Umbilical Cord Blood Derived Endothelial Progenitor Cells: Isolation, Characterization, and Adhesion Potential in Vitro and in Vivo 

Brown, Melissa Ann (2009)
The number one cause of death in the industrialized world, atherosclerosis, can be treated through a variety of methods: angioplasty, stenting, vein graft bypass, synthetic grafts, and maybe one day tissue engineering vessels ...
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AuthorBrochu, Alice (2)Garcia Quiroz, Felipe (2)Hwang, Priscilla Y. (2)Kocak, Daniel Dewran (2)Lo, JY (2)Schaal, Jeffrey Laurence (2)Sinclair, Steven Michael (2)Zhang, Carolyn (2)Abzug, Zachary Mitchell (1)Adams, Michael (1)... View MoreDate Issued2010 - 2020 (332)2006 - 2009 (42)TypeDissertation (332)Master's thesis (41)Conference (1)Journal article (1)SubjectBiomedical engineering (254)Engineering, Biomedical (58)Medical imaging (25)Biomedical Engineering (23)Biomechanics (22)Medical imaging and radiology (19)Neurosciences (19)Optics (15)Ultrasound (15)Materials Science (13)... View MoreDepartment
Biomedical Engineering (374)
Affiliation of Duke Author(s)Biomedical Engineering (5)Duke (5)Pratt School of Engineering (5)Clinical Science Departments (4)School of Medicine (4)Duke Cancer Institute (2)Electrical and Computer Engineering (2)Institutes and Centers (2)Radiology (2)Duke Institute for Brain Sciences (1)... View More
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