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Now showing items 11-20 of 374
Generation of Functional Hepatocyte-Like Cells (HLCs) from Human Adipose-Derived Stem Cells (ADSCs) in 2D and 3D
(2019)
Mortality and morbidity rates caused by acute liver failure (ALF), acute-on-chronic
liver failure (ACLF) and chronic liver disease continue to rise because of drug induced
failure or viral hepatitis, currently with 2,000 ...
Design, Fabrication, and Implementation of Voxel-Based 3D Printed Heterogeneous Lung Lesion Phantoms for Assessment of CT Imaging Conditions on Texture Quantification
(2016)
Realistic virtual lesion models are valuable in medical imaging applications including
phantom design and observer studies. Radiologic diagnostic information rarely include
lesion texture due to the fact that texture ...
A Tissue-Engineered Microvascular System to Evaluate Vascular Progenitor Cells for Angiogenic Therapies
(2015)
The ability of tissue engineered constructs to replace diseased or damaged organs
is limited without the incorporation of a functional vascular system. To design microvasculature
that recapitulates the vascular niche functions ...
Micro-Anatomical Quantitative Imaging Towards Enabling Automated Diagnosis of Thick Tissues at the Point of Care
(2015)
Histopathology is the clinical standard for tissue diagnosis. However, histopathology
has several limitations including that it requires tissue processing, which can take
30 minutes or more, and requires a highly trained ...
Evaluation of a Low Cost, Downstream Purification Process for Griffithsin - a Potential Broad Spectrum Viral Entry Inhibitor Produced in Engineered E. coli
(2017)
HIV infections remain a major public health issue with no current cure: in 2015, the
disease led to the deaths of 1.1 million people [1]. A viable preventative is Griffithsin
(GRFT), a lectin that binds and neutralizes the ...
Peptide-Based Stimuli-Responsive Materials for Bioanalytical Applications
(2017)
Surfaces with switchable properties in response to external stimuli (e.g., temperature
and pH) have attracted substantial research interest because of their ability to modulate
biomolecule activity, protein immobilization, ...
Microfluidics-generated Double Emulsion Platform for High-Throughput Screening and Multicellular Spheroid Production with Controllable Microenvironment
(2015)
High-throughput processing technologies hold critical position in biomedical research.
These include screening of cellular response based on phenotypic difference and production
of homogeneous chemicals and biologicals for ...
Optimized approach to decision fusion of heterogeneous data for breast cancer diagnosis.
(Med Phys, 2006-08)
As more diagnostic testing options become available to physicians, it becomes more
difficult to combine various types of medical information together in order to optimize
the overall diagnosis. To improve diagnostic performance, ...
Non-uniform Interstitial Loading in Cardiac Microstructure During Impulse Propagation
(2009)
Impulse propagation in cardiac muscle is determined not only by the excitable properties
of the myocyte membrane, but also by the gross and fine structure of cardiac muscle.
Ionic diffusion pathways are defined by the muscle's ...
Umbilical Cord Blood Derived Endothelial Progenitor Cells: Isolation, Characterization, and Adhesion Potential in Vitro and in Vivo
(2009)
The number one cause of death in the industrialized world, atherosclerosis, can be
treated through a variety of methods: angioplasty, stenting, vein graft bypass, synthetic
grafts, and maybe one day tissue engineering vessels ...