Mortality and morbidity rates caused by acute liver failure (ALF), acute-on-chronic liver failure (ACLF) and chronic liver disease continue to rise because of drug induced failure or viral hepatitis, currently with 2,000 ...

Realistic virtual lesion models are valuable in medical imaging applications including phantom design and observer studies. Radiologic diagnostic information rarely include lesion texture due to the fact that texture ...

The ability of tissue engineered constructs to replace diseased or damaged organs is limited without the incorporation of a functional vascular system. To design microvasculature that recapitulates the vascular niche functions ...

Histopathology is the clinical standard for tissue diagnosis. However, histopathology has several limitations including that it requires tissue processing, which can take 30 minutes or more, and requires a highly trained ...

HIV infections remain a major public health issue with no current cure: in 2015, the disease led to the deaths of 1.1 million people [1]. A viable preventative is Griffithsin (GRFT), a lectin that binds and neutralizes the ...

Surfaces with switchable properties in response to external stimuli (e.g., temperature and pH) have attracted substantial research interest because of their ability to modulate biomolecule activity, protein immobilization, ...

High-throughput processing technologies hold critical position in biomedical research. These include screening of cellular response based on phenotypic difference and production of homogeneous chemicals and biologicals for ...

As more diagnostic testing options become available to physicians, it becomes more difficult to combine various types of medical information together in order to optimize the overall diagnosis. To improve diagnostic performance, ...

Impulse propagation in cardiac muscle is determined not only by the excitable properties of the myocyte membrane, but also by the gross and fine structure of cardiac muscle. Ionic diffusion pathways are defined by the muscle's ...

The number one cause of death in the industrialized world, atherosclerosis, can be treated through a variety of methods: angioplasty, stenting, vein graft bypass, synthetic grafts, and maybe one day tissue engineering vessels ...