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Brain activity during episodic retrieval of autobiographical and laboratory events: an fMRI study using a novel photo paradigm.

dc.contributor.author Cabeza, Roberto
dc.contributor.author Prince, Steve E
dc.contributor.author Daselaar, Sander M
dc.contributor.author Greenberg, Daniel L
dc.contributor.author Budde, Matthew
dc.contributor.author Dolcos, Florin
dc.contributor.author LaBar, Kevin S
dc.contributor.author Rubin, David C
dc.coverage.spatial United States
dc.date.accessioned 2015-05-20T02:25:55Z
dc.date.issued 2004-11
dc.identifier https://www.ncbi.nlm.nih.gov/pubmed/15622612
dc.identifier.issn 0898-929X
dc.identifier.uri https://hdl.handle.net/10161/10110
dc.description.abstract Functional neuroimaging studies of episodic memory retrieval generally measure brain activity while participants remember items encountered in the laboratory ("controlled laboratory condition") or events from their own life ("open autobiographical condition"). Differences in activation between these conditions may reflect differences in retrieval processes, memory remoteness, emotional content, retrieval success, self-referential processing, visual/spatial memory, and recollection. To clarify the nature of these differences, a functional MRI study was conducted using a novel "photo paradigm," which allows greater control over the autobiographical condition, including a measure of retrieval accuracy. Undergraduate students took photos in specified campus locations ("controlled autobiographical condition"), viewed in the laboratory similar photos taken by other participants (controlled laboratory condition), and were then scanned while recognizing the two kinds of photos. Both conditions activated a common episodic memory network that included medial temporal and prefrontal regions. Compared with the controlled laboratory condition, the controlled autobiographical condition elicited greater activity in regions associated with self-referential processing (medial prefrontal cortex), visual/spatial memory (visual and parahippocampal regions), and recollection (hippocampus). The photo paradigm provides a way of investigating the functional neuroanatomy of real-life episodic memory under rigorous experimental control.
dc.language eng
dc.publisher MIT Press - Journals
dc.relation.ispartof J Cogn Neurosci
dc.subject Adolescent
dc.subject Adult
dc.subject Arousal
dc.subject Brain Mapping
dc.subject Cerebral Cortex
dc.subject Female
dc.subject Hippocampus
dc.subject Humans
dc.subject Magnetic Resonance Imaging
dc.subject Male
dc.subject Mental Recall
dc.subject Photic Stimulation
dc.subject Photography
dc.subject Reference Values
dc.subject Self Concept
dc.title Brain activity during episodic retrieval of autobiographical and laboratory events: an fMRI study using a novel photo paradigm.
dc.type Journal article
duke.contributor.id Cabeza, Roberto|0274780
duke.contributor.id LaBar, Kevin S|0230529
duke.contributor.id Rubin, David C|0096042
pubs.author-url https://www.ncbi.nlm.nih.gov/pubmed/15622612
pubs.begin-page 1583
pubs.end-page 1594
pubs.issue 9
pubs.organisational-group Center for Cognitive Neuroscience
pubs.organisational-group Center for Population Health & Aging
pubs.organisational-group Clinical Science Departments
pubs.organisational-group Duke
pubs.organisational-group Duke Institute for Brain Sciences
pubs.organisational-group Duke Population Research Institute
pubs.organisational-group Duke Science & Society
pubs.organisational-group Duke-UNC Center for Brain Imaging and Analysis
pubs.organisational-group Initiatives
pubs.organisational-group Institutes and Centers
pubs.organisational-group Institutes and Provost's Academic Units
pubs.organisational-group Psychiatry & Behavioral Sciences
pubs.organisational-group Psychiatry & Behavioral Sciences, Geriatric Behavioral Health
pubs.organisational-group Psychiatry & Behavioral Sciences, Translational Neuroscience
pubs.organisational-group Psychology and Neuroscience
pubs.organisational-group Sanford School of Public Policy
pubs.organisational-group School of Medicine
pubs.organisational-group Trinity College of Arts & Sciences
pubs.organisational-group University Institutes and Centers
pubs.publication-status Published
pubs.volume 16
duke.contributor.orcid Cabeza, Roberto|0000-0001-7999-1182
duke.contributor.orcid LaBar, Kevin S|0000-0002-8253-5417


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