Puzzling thoughts for H. M.: can new semantic information be anchored to old semantic memories?
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Researchers currently debate whether new semantic knowledge can be learned and retrieved despite extensive damage to medial temporal lobe (MTL) structures. The authors explored whether H. M., a patient with amnesia, could acquire new semantic information in the context of his lifelong hobby of solving crossword puzzles. First, H. M. was tested on a series of word-skills tests believed important in solving crosswords. He also completed 3 new crosswords: 1 puzzle testing pre-1953 knowledge, another testing post-1953 knowledge, and another combining the 2 by giving postoperative semantic clues for preoperative answers. From the results, the authors concluded that H. M. can acquire new semantic knowledge, at least temporarily, when he can anchor it to mental representations established preoperatively.
Published Version (Please cite this version)10.1037/0894-4220.127.116.116
Publication InfoCorkin, S; Einstein, G; Kensinger, EA; Krendl, A; Locascio, JJ; Rubin, David C; ... Tupler, LA (2004). Puzzling thoughts for H. M.: can new semantic information be anchored to old semantic memories?. Neuropsychology, 18(4). pp. 756-769. 10.1037/0894-418.104.22.1686. Retrieved from https://hdl.handle.net/10161/10113.
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Juanita M. Kreps Professor of Psychology and Neuroscience
For .pdfs of all publications click here My main research interest has been in long-term memory, especially for complex (or "real-world") stimuli. This work includes the study of autobiographical memory
Associate Professor in Psychiatry and Behavioral Sciences
My principal research interest concerns brain-behavior relationships, both in normals and in psychiatric populations. Methods of study include magnetic resonance imaging (MRI) and spectroscopy (MRS), neuropsychological investigations, psychopharmacological studies, cognitive-science paradigms, and methodological inquiries. More specifically, topics of interest include lesion and morphometric studies of discrete brain regions as they relate to cognitive and ot
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