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Advances in understanding mechanisms of thalamic relays in cognition and behavior.

dc.contributor.author Mitchell, Anna S
dc.contributor.author Sherman, S Murray
dc.contributor.author Sommer, Marc A
dc.contributor.author Mair, Robert G
dc.contributor.author Vertes, Robert P
dc.contributor.author Chudasama, Yogita
dc.coverage.spatial United States
dc.date.accessioned 2015-06-12T00:30:16Z
dc.date.issued 2014-11-12
dc.identifier http://www.ncbi.nlm.nih.gov/pubmed/25392501
dc.identifier 34/46/15340
dc.identifier.uri https://hdl.handle.net/10161/10212
dc.description.abstract The main impetus for a mini-symposium on corticothalamic interrelationships was the recent number of studies highlighting the role of the thalamus in aspects of cognition beyond sensory processing. The thalamus contributes to a range of basic cognitive behaviors that include learning and memory, inhibitory control, decision-making, and the control of visual orienting responses. Its functions are deeply intertwined with those of the better studied cortex, although the principles governing its coordination with the cortex remain opaque, particularly in higher-level aspects of cognition. How should the thalamus be viewed in the context of the rest of the brain? Although its role extends well beyond relaying of sensory information from the periphery, the main function of many of its subdivisions does appear to be that of a relay station, transmitting neural signals primarily to the cerebral cortex from a number of brain areas. In cognition, its main contribution may thus be to coordinate signals between diverse regions of the telencephalon, including the neocortex, hippocampus, amygdala, and striatum. This central coordination is further subject to considerable extrinsic control, for example, inhibition from the basal ganglia, zona incerta, and pretectal regions, and chemical modulation from ascending neurotransmitter systems. What follows is a brief review on the role of the thalamus in aspects of cognition and behavior, focusing on a summary of the topics covered in a mini-symposium held at the Society for Neuroscience meeting, 2014.
dc.language eng
dc.publisher Society for Neuroscience
dc.relation.ispartof J Neurosci
dc.relation.isversionof 10.1523/JNEUROSCI.3289-14.2014
dc.subject Animals
dc.subject Behavior
dc.subject Cerebral Cortex
dc.subject Cognition
dc.subject Humans
dc.subject Learning
dc.subject Neural Pathways
dc.subject Thalamus
dc.title Advances in understanding mechanisms of thalamic relays in cognition and behavior.
dc.type Journal article
duke.contributor.id Sommer, Marc A|0522637
pubs.author-url http://www.ncbi.nlm.nih.gov/pubmed/25392501
pubs.begin-page 15340
pubs.end-page 15346
pubs.issue 46
pubs.organisational-group Basic Science Departments
pubs.organisational-group Biomedical Engineering
pubs.organisational-group Center for Cognitive Neuroscience
pubs.organisational-group Duke
pubs.organisational-group Duke Institute for Brain Sciences
pubs.organisational-group Institutes and Provost's Academic Units
pubs.organisational-group Neurobiology
pubs.organisational-group Pratt School of Engineering
pubs.organisational-group School of Medicine
pubs.organisational-group University Institutes and Centers
pubs.publication-status Published
pubs.volume 34
dc.identifier.eissn 1529-2401
duke.contributor.orcid Sommer, Marc A|0000-0001-5061-763X


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