Botulinum toxin type A injections for the management of muscle tightness following total hip arthroplasty: a case series.
Abstract
BACKGROUND: Development of hip adductor, tensor fascia lata, and rectus femoris muscle
contractures following total hip arthroplasties are quite common, with some patients
failing to improve despite treatment with a variety of non-operative modalities. The
purpose of the present study was to describe the use of and patient outcomes of botulinum
toxin injections as an adjunctive treatment for muscle tightness following total hip
arthroplasty. METHODS: Ten patients (14 hips) who had hip adductor, abductor, and/or
flexor muscle contractures following total arthroplasty and had been refractory to
physical therapeutic efforts were treated with injection of botulinum toxin A. Eight
limbs received injections into the adductor muscle, 8 limbs received injections into
the tensor fascia lata muscle, and 2 limbs received injection into the rectus femoris
muscle, followed by intensive physical therapy for 6 weeks. RESULTS: At a mean final
follow-up of 20 months, all 14 hips had increased range in the affected arc of motion,
with a mean improvement of 23 degrees (range, 10 to 45 degrees). Additionally all
hips had an improvement in hip scores, with a significant increase in mean score from
74 points (range, 57 to 91 points) prior to injection to a mean of 96 points (range,
93 to 98) at final follow-up. There were no serious treatment-related adverse events.
CONCLUSION: Botulinum toxin A injections combined with intensive physical therapy
may be considered as a potential treatment modality, especially in difficult cases
of muscle tightness that are refractory to standard therapy.
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https://hdl.handle.net/10161/10372Published Version (Please cite this version)
10.1186/1749-799X-4-34Publication Info
Bhave, Anil; Zywiel, Michael G; Ulrich, Slif D; McGrath, Mike S; Seyler, Thorsten
M; Marker, David R; ... Mont, Michael A (2009). Botulinum toxin type A injections for the management of muscle tightness following
total hip arthroplasty: a case series. J Orthop Surg Res, 4. pp. 34. 10.1186/1749-799X-4-34. Retrieved from https://hdl.handle.net/10161/10372.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Thorsten Markus Seyler
Associate Professor in Orthopaedic Surgery
Based on a recent market research survey, the U.S. demand for implantable medical
devices is forecast to increase 7.7% annually to $52 billion in 2015. While orthopedic
implants remain the largest segment, implantable devices are frequently used in urology,
cardiovascular specialties, neurology, gynecology, and otolaryngology. With the increased
usage of implantable devices, the number of biofilm-associated infections has emerged
as a significant clinical problem because biofilms are oft

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