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Characterizing the Switching Thresholds of Magnetophoretic Transistors.

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Date
2015-10-28
Authors
Abedini-Nassab, Roozbeh
Joh, Daniel Y
Van Heest, Melissa A
Yi, John S
Baker, Cody
Taherifard, Zohreh
Margolis, David M
Garcia, J Victor
Chilkoti, Ashutosh
Murdoch, David M
Yellen, Benjamin B
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(11 total)
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Abstract
The switching thresholds of magnetophoretic transistors for sorting cells in microfluidic environments are characterized. The transistor operating conditions require short 20-30 mA pulses of electrical current. By demonstrating both attractive and repulsive transistor modes, a single transistor architecture is used to implement the full write cycle for importing and exporting single cells in specified array sites.
Type
Journal article
Subject
magnetism
microfabrication
microfluidics
single cells
transistors
Antigens, CD4
Equipment Design
Finite Element Analysis
Humans
Magnetic Phenomena
Microfluidic Analytical Techniques
Models, Theoretical
Printing, Three-Dimensional
Semiconductors
T-Lymphocytes
Permalink
https://hdl.handle.net/10161/10827
Published Version (Please cite this version)
10.1002/adma.201502352
Publication Info
Abedini-Nassab, Roozbeh; Joh, Daniel Y; Van Heest, Melissa A; Yi, John S; Baker, Cody; Taherifard, Zohreh; ... Yellen, Benjamin B (2015). Characterizing the Switching Thresholds of Magnetophoretic Transistors. Adv Mater, 27(40). pp. 6176-6180. 10.1002/adma.201502352. Retrieved from https://hdl.handle.net/10161/10827.
This is constructed from limited available data and may be imprecise. To cite this article, please review & use the official citation provided by the journal.
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Scholars@Duke

Chilkoti

Ashutosh Chilkoti

Alan L. Kaganov Distinguished Professor of Biomedical Engineering
Ashutosh Chilkoti is the Alan L. Kaganov Professor of Biomedical Engineering and Chair of the Department of Biomedical Engineering at Duke University. My research in biomolecular engineering and biointerface science focuses on the development of new molecular tools and technologies that borrow from molecular biology, protein engineering, polymer chemistry and surface science that we then exploit for the development of applications that span the range from bioseparations, plasmonic bio
Murdoch

David Martin Murdoch

Associate Professor of Medicine
As a physician and researcher, my career has been driven by a passion for linking the basic and clinical sciences with the primary goal of understanding the disease pathogenesis. Through my training in epidemiology, basic science immunology, and clinical medicine, I have acquired a breadth of experience, knowledge, collaborators, and an adaptability which has culminated in a research focus on the reconstitution of immune responses and systemic inflammation in immunocompromised patients and vulne
Yellen

Benjamin Yellen

Associate Professor in the Department of Mechanical Engineering and Materials Science
Yellen's group is interested in developing highly parallel mechanisms for controlling the transport and assembly of ensembles of objects ranging from micron-sized colloidal particles to single cells.  As of 2013, Professor Yellen is active in two main areas of research:1) Development of single cell analysis tools using magnetic circuits. The goal of this project is to develop an automated single cell analysis platform that allows for highly flexible and highly paralle
Yi

John S Yi

Adjunct Assistant Professor in the Department of Surgery
I am an immunologist, with a focus to characterize the immune system in response to infectious and non-infectious diseases including cancer, HIV, autoimmune disease, and transplantation. My goals are to identify novel biomarkers/immune signatures that clinicians can utilize to diagnosis, predict disease outcomes, and determine patients' response to treatment. 
Alphabetical list of authors with Scholars@Duke profiles.
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