HIV-1 envelope gp41 broadly neutralizing antibodies: hurdles for vaccine development.
Type
Journal articleSubject
AIDS VaccinesAntibodies, Neutralizing
Autoantibodies
Drug Discovery
HIV Antibodies
HIV Envelope Protein gp41
HIV Infections
HIV-1
Humans
Immune Tolerance
Mutation
Permalink
https://hdl.handle.net/10161/10898Published Version (Please cite this version)
10.1371/journal.ppat.1004073Publication Info
Verkoczy, Laurent; Kelsoe, Garnett; & Haynes, Barton F (2014). HIV-1 envelope gp41 broadly neutralizing antibodies: hurdles for vaccine development.
PLoS Pathog, 10(5). pp. e1004073. 10.1371/journal.ppat.1004073. Retrieved from https://hdl.handle.net/10161/10898.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
Collections
More Info
Show full item recordScholars@Duke
Barton Ford Haynes
Frederic M. Hanes Distinguished Professor of Medicine
Barton F. Haynes, M.D. is the Frederic M. Hanes Professor of Medicine and Immunology,
and Director of the Duke Human Vaccine Institute. Prior to leading the DHVI, Dr. Haynes
served as Chief of the Division of Rheumatology, Allergy and Clinical Immunology,
and later as Chair of the Department of Medicine. As Director of the Duke Human Vaccine
Institute, Bart Haynes is leading a team of investigators working on vaccines for
emerging infections, including tuberculosis, pandemic influenza, emergi
Garnett H. Kelsoe
James B. Duke Distinguished Professor of Immunology
1. Lymphocyte development and antigen-driven diversification of immunoglobulin and
T cell antigen receptor genes. 2. The germinal center reaction and mechanisms for
clonal selection and self - tolerance. The origins of autoimmunity. 3. Interaction
of innate- and adaptive immunity and the role of inflammation in lymphoid organogenesis.
4. The role of secondary V(D)J gene rearrangment in lymphocyte development and malignancies.
5. Mathematical modeling of immune responses,
Laurent Karl Verkoczy
Adjunct Professor in the Department of Medicine
Laurent Verkoczy, PhD is Associate Professor of Medicine and Pathology at Duke University
Medical Center. Dr.Verkoczy directs the Laboratory of B-cell Immunoregulation at the
Duke Human Vaccine Institute and also serves as a B-cell Focus Investigator in Duke’s
Center for HIV/AIDS Vaccine Immunology & Immunogen Discovery (CHAVI-ID) consortium.
He obtained his Ph.D. in Immunology from the University of Toronto in 2000 and completed
post-doctoral studies at The S
This author no longer has a Scholars@Duke profile, so the information shown here reflects
their Duke status at the time this item was deposited.
Alphabetical list of authors with Scholars@Duke profiles.

Articles written by Duke faculty are made available through the campus open access policy. For more information see: Duke Open Access Policy
Rights for Collection: Scholarly Articles
Works are deposited here by their authors, and represent their research and opinions, not that of Duke University. Some materials and descriptions may include offensive content. More info