A case of frontal neuropsychological and neuroimaging signs following multiple primary-blast exposure.
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Blast-related traumatic brain injury (TBI) from the Afghanistan and Iraq wars represents a significant medical concern for troops and veterans. To better understand the consequences of primary-blast injury in humans, we present a case of a Marine exposed to multiple primary blasts during his 14-year military career. The neuropsychological profile of this formerly high-functioning veteran suggested primarily executive dysfunction. Diffusion-tensor imaging revealed white-matter pathology in long fiber tracks compared with a composite fractional-anisotropy template derived from a veteran reference control group without TBI. This study supports the existence of primary blast-induced neurotrauma in humans and introduces a neuroimaging technique with potential to discriminate multiple-blast TBI.
Diffusion Tensor Imaging
Magnetic Resonance Imaging
Published Version (Please cite this version)10.1080/13554794.2011.588181
Publication InfoHayes, JP; Morey, Rajendra A; & Tupler, LA (2012). A case of frontal neuropsychological and neuroimaging signs following multiple primary-blast exposure. Neurocase, 18(3). pp. 258-269. 10.1080/13554794.2011.588181. Retrieved from https://hdl.handle.net/10161/10983.
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Associate Professor of Psychiatry and Behavioral Sciences
Research in my lab is focused on brain changes associated with posttraumatic stress disorder (PTSD), traumatic brain injury (TBI), and other neuropsychiatric disorders. We apply several advanced methods for understanding brain function including functional MRI, structural MRI, diffusion tensor imaging, and genetic effects.
Associate Professor in Psychiatry and Behavioral Sciences
My principal research interest concerns brain-behavior relationships, both in normals and in psychiatric populations. Methods of study include magnetic resonance imaging (MRI) and spectroscopy (MRS), neuropsychological investigations, psychopharmacological studies, cognitive-science paradigms, and methodological inquiries. More specifically, topics of interest include lesion and morphometric studies of discrete brain regions as they relate to cognitive and ot
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