The Impact of Worsening Heart Failure in the United States.
Abstract
In-hospital worsening heart failure represents a clinical scenario wherein a patient
hospitalized for acute heart failure experiences a worsening of their condition, requiring
escalation of therapy. Worsening heart failure is associated with worse in-hospital
and postdischarge outcomes. Worsening heart failure is increasingly being used as
an endpoint or combined endpoint in clinical trials, as it is unique to episodes of
acute heart failure and captures an important event during the inpatient course. While
prediction models have been developed to identify worsening heart failure, there are
no known FDA-approved medications associated with decreased worsening heart failure.
Continued study is warranted.
Type
Journal articleSubject
Clinical trialsMedications
Outcomes
Worsening heart failure
Acute Disease
Clinical Trials as Topic
Heart Failure
Hospitalization
Humans
Incidence
Registries
United States
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https://hdl.handle.net/10161/11002Published Version (Please cite this version)
10.1016/j.hfc.2015.07.004Publication Info
Cooper, Lauren B; DeVore, Adam D; & Michael Felker, G (2015). The Impact of Worsening Heart Failure in the United States. Heart Fail Clin, 11(4). pp. 603-614. 10.1016/j.hfc.2015.07.004. Retrieved from https://hdl.handle.net/10161/11002.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Lauren Beth Cooper
Adjunct Associate in the Department of Medicine
Adam David DeVore
Associate Professor of Medicine
Adam D. DeVore, MD, MHS
Dr. DeVore is a cardiologist and Associate Professor of Medicine in the Department
of Medicine, Division of Cardiology, at Duke University School of Medicine. His clinical
interests include caring for patients and families with heart failure, including those
with left ventricular assist devices and heart transplants. He is involved in and
leads multiple large studies of patients with heart failure at both Duke University
Medical Center and the
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