Acute infectious morbidity in multiple gestation.
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OBJECTIVES: Physiologic and immunologic changes in pregnancy result in increased susceptibility to infection. These shifts are more pronounced in pregnancies complicated by multiple gestation. The objective of this study was to determine the association between multiple gestation and risk of infectious morbidity. STUDY DESIGN: The Nationwide Inpatient Sample for the years 2008-2010 was used to identify pregnant women during admission for delivery with International Classification of Diseases codes. Logistic regression was used to compute odds ratios and 95% confidence intervals for demographic data, preexisting medical conditions, and acute medical and infectious complications for women with multiple versus singleton gestations. RESULTS: Among women with multiple gestation, 38.4 per 1,000 women had an infectious complication compared to 12.8 per 1,000 women with singletons. The most significant infectious morbidity associated with multiple gestation was intestinal infections, pyelonephritis, influenza, and pneumonia. After controlling for confounding variables, infectious complications at delivery persisted for women with multiples, though the association was dependent on mode of delivery. CONCLUSIONS: Women with multiple gestations are at increased risk for infectious morbidity identified at the time of delivery. This association was diminished among women who had a cesarean suggesting that operative delivery is not responsible for this association.
Pregnancy Complications, Infectious
Published Version (Please cite this version)10.1155/2015/173261
Publication InfoDotters-Katz, Sarah K; Patel, Emily; Grotegut, Chad A; & Heine, R Phillips (2015). Acute infectious morbidity in multiple gestation. Infect Dis Obstet Gynecol, 2015. pp. 173261. 10.1155/2015/173261. Retrieved from https://hdl.handle.net/10161/11091.
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Assistant Professor of Obstetrics and Gynecology
My passion is for medical education. As a resident, I was recognized for excellence in teaching by the medical students during all four years of my training, and completed the “Resident as Teacher” program during that time as well. I have obtained my Masters of Medical Health Professions Education from Eastern Virginia Medical School from 2016-2017. During that time, I also completed the University of North Carolina Faculty Scholars program and was inducted into the University of
Associate Professor of Obstetrics and Gynecology
I am a specialist in maternal-fetal medicine, which is a subspecialty of OB/GYN that focuses on the care of women with high-risk pregnancies. I serve as the Medical Director of the Labor and Delivery Unit at Duke University Hospital. In that role, and together with our outstanding unit team members, we have the opportunity to help women and their families ensure that they have the safest and best labor and delivery experience possible. My specific clinical int
Professor of Obstetrics and Gynecology
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