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Understanding human variation in infectious disease susceptibility through clinical and cellular GWAS.
Type
Journal articleSubject
Communicable DiseasesGenetic Predisposition to Disease
Genetic Variation
Genome-Wide Association Study
Humans
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https://hdl.handle.net/10161/11105Published Version (Please cite this version)
10.1371/journal.ppat.1003424Publication Info
(2013). Understanding human variation in infectious disease susceptibility through clinical
and cellular GWAS. PLoS Pathog, 9(8). pp. e1003424. 10.1371/journal.ppat.1003424. Retrieved from https://hdl.handle.net/10161/11105.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Dennis Ko
Associate Professor in Molecular Genetics and Microbiology
Using Pathogens to Decipher Genetic Variation Connecting Cell Biology and Disease
SusceptibilityDespite improvements in public health, advancements in vaccines, and
the development of many classes of antibiotics, infectious disease is still responsible
for over a quarter of all deaths worldwide. However, even for the most devastating
of pandemics, individuals demonstrate a large variability in the severity of infection.
The long-term goal of the lab is to understand the ge
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