Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2.
Disease Models, Animal
Enzyme-Linked Immunosorbent Assay
Lupus Erythematosus, Systemic
Mice, Inbred Strains
Receptors, Complement 3b
Receptors, Complement 3d
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The Complement Receptors C3aR and C5aR Are a New Class of Immune Checkpoint Receptor in Cancer Immunotherapy. Wang, Yu; Zhang, Hui; He, You-Wen (Frontiers in Immunology, 2019-01)Cancer immunotherapy has made remarkable clinical advances in recent years. Antibodies targeting the immune checkpoint receptors PD-1 and CTLA-4 and adoptive cell therapy (ACT) based on ex vivo expanded peripheral CTLs, ...
Ahern, Perciliz Lumaban Tan (2016)Age-related macular degeneration is one of the leading causes of vision loss in the world. While identification of various environmental risk factors including but not limited to smoking, ethnicity, and diet have been reported ...
Differential Killing of Salmonella enterica Serovar Typhi by Antibodies Targeting Vi and Lipopolysaccharide O:9 Antigen. Hart, Peter J; O'Shaughnessy, Colette M; Siggins, Matthew K; Bobat, Saeeda; Kingsley, Robert A; Goulding, David A; Crump, John A; ... (12 authors) (PLoS One, 2016)Salmonella enterica serovar Typhi expresses a capsule of Vi polysaccharide, while most Salmonella serovars, including S. Enteritidis and S. Typhimurium, do not. Both S. Typhi and S. Enteritidis express the lipopolysaccharide ...