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3-Hydroxyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin)-induced 28-kDa interleukin-1ß interferes with mature IL-1ß signaling
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https://hdl.handle.net/10161/11513Collections
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Donghai Wang
Assistant Professor in Medicine
Inflammation underlies a variety of human diseases such as obesity, diabetes, cardiovascular
diseases, neurodegenerative diseases, arthritis and cancer. Together, these diseases
constitute a major challenge to the well being of modern human society. Understanding
the fundamental mechanisms of inflammation may provide rationales for designing novel
interventions to treat these maladies. Autoinflammatory diseases are an emerging family
of illness, characterized by dysregulation of innate immune re

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