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The effectiveness of low-level laser therapy for nonspecific chronic low back pain: a systematic review and meta-analysis.

dc.contributor.author Chen, J
dc.contributor.author Huang, Z
dc.contributor.author Kraus, Virginia Byers
dc.contributor.author Ma, J
dc.contributor.author Pei, F
dc.contributor.author Shen, B
dc.coverage.spatial England
dc.date.accessioned 2016-02-01T18:30:04Z
dc.date.issued 2015-12-15
dc.identifier http://www.ncbi.nlm.nih.gov/pubmed/26667480
dc.identifier 10.1186/s13075-015-0882-0
dc.identifier.uri http://hdl.handle.net/10161/11582
dc.description.abstract BACKGROUND: In recent decades, low-level laser therapy (LLLT) has been widely used to relieve pain caused by different musculoskeletal disorders. Though widely used, its reported therapeutic outcomes are varied and conflicting. Results similarly conflict regarding its usage in patients with nonspecific chronic low back pain (NSCLBP). This study investigated the efficacy of low-level laser therapy (LLLT) for the treatment of NSCLBP by a systematic literature search with meta-analyses on selected studies. METHOD: MEDLINE, EMBASE, ISI Web of Science and Cochrane Library were systematically searched from January 2000 to November 2014. Included studies were randomized controlled trials (RCTs) written in English that compared LLLT with placebo treatment in NSCLBP patients. The efficacy effect size was estimated by the weighted mean difference (WMD). Standard random-effects meta-analysis was used, and inconsistency was evaluated by the I-squared index (I(2)). RESULTS: Of 221 studies, seven RCTs (one triple-blind, four double-blind, one single-blind, one not mentioning blinding, totaling 394 patients) met the criteria for inclusion. Based on five studies, the WMD in visual analog scale (VAS) pain outcome score after treatment was significantly lower in the LLLT group compared with placebo (WMD = -13.57 [95 % CI = -17.42, -9.72], I(2) = 0 %). No significant treatment effect was identified for disability scores or spinal range of motion outcomes. CONCLUSIONS: Our findings indicate that LLLT is an effective method for relieving pain in NSCLBP patients. However, there is still a lack of evidence supporting its effect on function.
dc.language eng
dc.relation.ispartof Arthritis Res Ther
dc.relation.isversionof 10.1186/s13075-015-0882-0
dc.subject Chronic Pain
dc.subject Humans
dc.subject Low Back Pain
dc.subject Low-Level Light Therapy
dc.title The effectiveness of low-level laser therapy for nonspecific chronic low back pain: a systematic review and meta-analysis.
dc.type Journal article
pubs.author-url http://www.ncbi.nlm.nih.gov/pubmed/26667480
pubs.begin-page 360
pubs.organisational-group Clinical Science Departments
pubs.organisational-group Duke
pubs.organisational-group Duke Molecular Physiology Institute
pubs.organisational-group Institutes and Centers
pubs.organisational-group Medicine
pubs.organisational-group Medicine, Rheumatology and Immunology
pubs.organisational-group Orthopaedics
pubs.organisational-group Pathology
pubs.organisational-group School of Medicine
pubs.publication-status Published online
pubs.volume 17
dc.identifier.eissn 1478-6362


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