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Frontal eye field neurons orthodromically activated from the superior colliculus.

dc.contributor.author Sommer, Marc A
dc.contributor.author Wurtz, RH
dc.coverage.spatial United States
dc.date.accessioned 2016-03-25T03:23:31Z
dc.date.issued 1998-12
dc.identifier http://www.ncbi.nlm.nih.gov/pubmed/9862927
dc.identifier.issn 0022-3077
dc.identifier.uri https://hdl.handle.net/10161/11756
dc.description.abstract Frontal eye field neurons orthodromically activated from the superior colliculus. J. Neurophysiol. 80: 3331-3333, 1998. Anatomical studies have shown that the frontal eye field (FEF) and superior colliculus (SC) of monkeys are reciprocally connected, and a physiological study described the signals sent from the FEF to the SC. Nothing is known, however, about the signals sent from the SC to the FEF. We physiologically identified and characterized FEF neurons that are likely to receive input from the SC. Fifty-two FEF neurons were found that were orthodromically activated by electrical stimulation of the intermediate or deeper layers of the SC. All the neurons that we tested (n = 34) discharged in response to visual stimulation. One-half also discharged when saccadic eye movements were made. This provides the first direct evidence that the ascending pathway from SC to FEF might carry visual- and saccade-related signals. Our findings support a hypothesis that the SC and the FEF interact bidirectionally during the events leading up to saccade generation.
dc.language eng
dc.relation.ispartof J Neurophysiol
dc.subject Animals
dc.subject Electric Stimulation
dc.subject Electrodes, Implanted
dc.subject Macaca mulatta
dc.subject Neurons
dc.subject Photic Stimulation
dc.subject Saccades
dc.subject Superior Colliculi
dc.subject Synapses
dc.subject Visual Fields
dc.subject Visual Pathways
dc.title Frontal eye field neurons orthodromically activated from the superior colliculus.
dc.type Journal article
pubs.author-url http://www.ncbi.nlm.nih.gov/pubmed/9862927
pubs.begin-page 3331
pubs.end-page 3335
pubs.issue 6
pubs.organisational-group Basic Science Departments
pubs.organisational-group Biomedical Engineering
pubs.organisational-group Center for Cognitive Neuroscience
pubs.organisational-group Duke
pubs.organisational-group Duke Institute for Brain Sciences
pubs.organisational-group Institutes and Provost's Academic Units
pubs.organisational-group Neurobiology
pubs.organisational-group Pratt School of Engineering
pubs.organisational-group School of Medicine
pubs.organisational-group University Institutes and Centers
pubs.publication-status Published
pubs.volume 80


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