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Correction for Eddy Current-Induced Echo-Shifting Effect in Partial-Fourier Diffusion Tensor Imaging.

dc.contributor.author Truong, TK
dc.contributor.author Song, AW
dc.contributor.author Chen, NK
dc.coverage.spatial United States
dc.date.accessioned 2016-05-10T16:13:01Z
dc.date.issued 2015
dc.identifier http://www.ncbi.nlm.nih.gov/pubmed/26413505
dc.identifier.uri http://hdl.handle.net/10161/11994
dc.description.abstract In most diffusion tensor imaging (DTI) studies, images are acquired with either a partial-Fourier or a parallel partial-Fourier echo-planar imaging (EPI) sequence, in order to shorten the echo time and increase the signal-to-noise ratio (SNR). However, eddy currents induced by the diffusion-sensitizing gradients can often lead to a shift of the echo in k-space, resulting in three distinct types of artifacts in partial-Fourier DTI. Here, we present an improved DTI acquisition and reconstruction scheme, capable of generating high-quality and high-SNR DTI data without eddy current-induced artifacts. This new scheme consists of three components, respectively, addressing the three distinct types of artifacts. First, a k-space energy-anchored DTI sequence is designed to recover eddy current-induced signal loss (i.e., Type 1 artifact). Second, a multischeme partial-Fourier reconstruction is used to eliminate artificial signal elevation (i.e., Type 2 artifact) associated with the conventional partial-Fourier reconstruction. Third, a signal intensity correction is applied to remove artificial signal modulations due to eddy current-induced erroneous T2(∗) -weighting (i.e., Type 3 artifact). These systematic improvements will greatly increase the consistency and accuracy of DTI measurements, expanding the utility of DTI in translational applications where quantitative robustness is much needed.
dc.language eng
dc.relation.ispartof Biomed Res Int
dc.relation.isversionof 10.1155/2015/185026
dc.subject Artifacts
dc.subject Brain
dc.subject Diffusion Tensor Imaging
dc.subject Fourier Analysis
dc.subject Humans
dc.subject Image Processing, Computer-Assisted
dc.title Correction for Eddy Current-Induced Echo-Shifting Effect in Partial-Fourier Diffusion Tensor Imaging.
dc.type Journal article
pubs.author-url http://www.ncbi.nlm.nih.gov/pubmed/26413505
pubs.begin-page 185026
pubs.organisational-group Basic Science Departments
pubs.organisational-group Biomedical Engineering
pubs.organisational-group Clinical Science Departments
pubs.organisational-group Duke
pubs.organisational-group Duke Cancer Institute
pubs.organisational-group Duke Institute for Brain Sciences
pubs.organisational-group Duke-UNC Center for Brain Imaging and Analysis
pubs.organisational-group Institutes and Centers
pubs.organisational-group Institutes and Provost's Academic Units
pubs.organisational-group Neurobiology
pubs.organisational-group Pratt School of Engineering
pubs.organisational-group Psychiatry & Behavioral Sciences
pubs.organisational-group Radiology
pubs.organisational-group School of Medicine
pubs.organisational-group University Institutes and Centers
pubs.publication-status Published
pubs.volume 2015
dc.identifier.eissn 2314-6141


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