Geographic Expansion of Lyme Disease in the Southeastern United States, 2000-2014.
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Background. The majority of Lyme disease cases in the United States are acquired on the east coast between northern Virginia and New England. In recent years the geographic extent of Lyme disease has been expanding, raising the prospect of Lyme disease becoming endemic in the southeast. Methods. We collected confirmed and probable cases of Lyme disease from 2000 through 2014 from the Virginia Department of Health and North Carolina Department of Public Health and entered them in a geographic information system. We performed spatial and spatiotemporal cluster analyses to characterize Lyme disease expansion. Results. There was a marked increase in Lyme disease cases in Virginia, particularly from 2007 onwards. Northern Virginia experienced intensification and geographic expansion of Lyme disease cases. The most notable area of expansion was to the southwest along the Appalachian Mountains with development of a new disease cluster in the southern Virginia mountain region. Conclusions. The geographic distribution of Lyme disease cases significantly expanded in Virginia between 2000 and 2014, particularly southward in the Virginia mountain ranges. If these trends continue, North Carolina can expect autochthonous Lyme disease transmission in its mountain region in the coming years.
Published Version (Please cite this version)10.1093/ofid/ofv143
Publication InfoAuwaerter, PG; Brinkerhoff, RJ; Broyhill, J; Fowler, Vance Garrison Jr; Gaines, DN; Lantos, Paul; ... Williams, Carl (2015). Geographic Expansion of Lyme Disease in the Southeastern United States, 2000-2014. Open Forum Infect Dis, 2(4). pp. ofv143. 10.1093/ofid/ofv143. Retrieved from https://hdl.handle.net/10161/12049.
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Florence McAlister Professor of Medicine
Determinants of Outcome in Patients with Staphylococcus aureus Bacteremia Pathogenesis of Bacterial Infections Infections due to Resistant Gram Positive Organisms Tropical medicine/International Health
Associate Professor of Medicine
I am interested in the spatial epidemiology of infectious diseases. My research utilizes geographic information systems (GIS) and geostatistical analyses to understand the spatial and spatiotemporal distribution of diseases, and their relationship with environmental and demographic factors. I currently have active studies evaluating the spatial distribution of numerous domestic and international infectious diseases, as well as studies of neighborhood health disparities in obstetrical care and bi
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