dc.contributor.author |
Ely, Sora |
|
dc.contributor.author |
Chandra, Abhinav |
|
dc.contributor.author |
Mani, Giselle |
|
dc.contributor.author |
Drake, Weiying |
|
dc.contributor.author |
Freeman, Debbie |
|
dc.contributor.author |
Limkakeng, Alexander T |
|
dc.coverage.spatial |
United States |
|
dc.date.accessioned |
2016-08-01T14:00:46Z |
|
dc.date.issued |
2013-02 |
|
dc.identifier |
http://www.ncbi.nlm.nih.gov/pubmed/22975283 |
|
dc.identifier |
S0736-4679(12)00870-0 |
|
dc.identifier.issn |
0736-4679 |
|
dc.identifier.uri |
https://hdl.handle.net/10161/12522 |
|
dc.description.abstract |
BACKGROUND: Determining which patients presenting to the Emergency Department (ED)
require further work-up for acute coronary syndrome (ACS) can be difficult. The utility
of routine observation for cardiac testing in low-risk young adult patients has been
questioned. STUDY OBJECTIVES: We investigated the rate of positive findings yielded
by routine cardiac observation unit work-up in patients aged 40 years or younger.
METHODS: This was a retrospective observational cohort study of patients aged 18-40
years who were evaluated for ACS in an ED-based observation unit. Data were collected
by trained abstractors from electronic medical records. RESULTS: A total of 362 patients
met inclusion criteria. Of those, 239 received stress testing, yielding five positive
and nine indeterminate results. One other patient had acute troponin elevation while
under observation. The positive stress test patients and troponin-elevated patient
underwent cardiac angiography. Only one positive stress test patient showed significant
coronary stenosis and received coronary interventions. In follow-up data, one patient
had an adverse cardiac outcome within 1 year of index visit, but no coronary interventions.
Thus, only 3 patients had adverse cardiac events, with only one patient warranting
intervention discovered by observation unit stress testing and a second via serial
cardiac markers. CONCLUSION: Routine observation of symptomatic young adults for ACS
had low yield. Observation identified one patient with acute cardiac marker elevation
and further stress testing identified only one patient with intervenable ACS, despite
a high false-positive rate. This suggests that observation and stress testing should
not be routinely performed in this demographic absent other high-risk features.
|
|
dc.language |
eng |
|
dc.relation.ispartof |
Journal of Emergency Medicine |
|
dc.relation.isversionof |
10.1016/j.jemermed.2012.07.048 |
|
dc.subject |
Acute Coronary Syndrome |
|
dc.subject |
Adolescent |
|
dc.subject |
Adult |
|
dc.subject |
Angioplasty, Balloon, Coronary |
|
dc.subject |
Cardiac Catheterization |
|
dc.subject |
Chest Pain |
|
dc.subject |
Cohort Studies |
|
dc.subject |
Coronary Angiography |
|
dc.subject |
Coronary Artery Bypass |
|
dc.subject |
Coronary Stenosis |
|
dc.subject |
Echocardiography, Stress |
|
dc.subject |
Emergency Service, Hospital |
|
dc.subject |
Female |
|
dc.subject |
Follow-Up Studies |
|
dc.subject |
Hospital Units |
|
dc.subject |
Humans |
|
dc.subject |
Magnetic Resonance Imaging, Cine |
|
dc.subject |
Male |
|
dc.subject |
Myocardial Infarction |
|
dc.subject |
Retrospective Studies |
|
dc.subject |
Tomography, X-Ray Computed |
|
dc.subject |
Troponin |
|
dc.subject |
Watchful Waiting |
|
dc.subject |
Young Adult |
|
dc.title |
Utility of observation units for young emergency department chest pain patients. |
|
dc.type |
Journal article |
|
duke.contributor.id |
Limkakeng, Alexander T|0410606 |
|
pubs.author-url |
http://www.ncbi.nlm.nih.gov/pubmed/22975283 |
|
pubs.begin-page |
306 |
|
pubs.end-page |
312 |
|
pubs.issue |
2 |
|
pubs.organisational-group |
Clinical Science Departments |
|
pubs.organisational-group |
Duke |
|
pubs.organisational-group |
School of Medicine |
|
pubs.organisational-group |
Surgery |
|
pubs.organisational-group |
Surgery, Emergency Medicine |
|
pubs.publication-status |
Published |
|
pubs.volume |
44 |
|
duke.contributor.orcid |
Limkakeng, Alexander T|0000-0002-9822-5595 |
|