New evidence in trauma resuscitation - is 1:1:1 the answer?
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Traumatic injury is a common problem, with over five million worldwide deaths from trauma per year. An estimated 10 to 20% of these deaths are potentially preventable with better control of bleeding. Damage control resuscitation involves early delivery of plasma and platelets as a primary resuscitation approach to minimize trauma-induced coagulopathy. Plasma, red blood cell and platelet ratios of 1:1:1 appear to be the best substitution for fresh whole blood; however, the current literature consists only of survivor bias-prone observational studies.
Published Version (Please cite this version)10.1186/2047-0525-2-13
Publication InfoMiller, Timothy Ellis (2013). New evidence in trauma resuscitation - is 1:1:1 the answer?. Perioper Med (Lond), 2(1). pp. 13. 10.1186/2047-0525-2-13. Retrieved from https://hdl.handle.net/10161/12555.
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Associate Professor of Anesthesiology
Clinical and research interests are Enhanced Recovery and Perioperative Medicine; with particular interests in fluid management, and perioperative optimization of the high-risk non-cardiac surgery patient.