Goal-directed or goal-misdirected - how should we interpret the literature?
Abstract
Goal-directed therapy (GDT) can be a vague term, meaning different things to different
people and, depending on the clinical environment, sometimes even different things
to the same person. It can refer to perioperative fluid management, clinicians driving
oxygen delivery to supramaximal values, early treatment of sepsis in the emergency
department, and even to restriction of perioperative crystalloids with the goal of
maintaining preadmission body weight. Understandably, strong opinions about GDT vary;
some clinicians consider it essential for perioperative care, others completely ineffective
in critically ill patients. This commentary aims to further position the excellent
review by Lees and colleagues in the context of the critical care and perioperative
setting.
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Journal articlePermalink
https://hdl.handle.net/10161/12557Published Version (Please cite this version)
10.1186/cc8884Publication Info
Roche, Anthony M; & Miller, Timothy E (2010). Goal-directed or goal-misdirected - how should we interpret the literature?. Crit Care, 14(2). pp. 129. 10.1186/cc8884. Retrieved from https://hdl.handle.net/10161/12557.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Timothy Ellis Miller
Professor of Anesthesiology
Clinical and research interests are Enhanced Recovery and Perioperative Medicine;
with particular interests in fluid management, and perioperative optimization of the
high-risk non-cardiac surgery patient.

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