Show simple item record

The roles of patents and research and development incentives in biopharmaceutical innovation.

dc.contributor.author DiMasi, Joseph A
dc.contributor.author Grabowski, Henry G
dc.contributor.author Long, Genia
dc.coverage.spatial United States
dc.date.accessioned 2016-09-13T07:36:43Z
dc.date.issued 2015-02
dc.identifier http://www.ncbi.nlm.nih.gov/pubmed/25646111
dc.identifier 34/2/302
dc.identifier.uri http://hdl.handle.net/10161/12744
dc.description.abstract Patents and other forms of intellectual property protection play essential roles in encouraging innovation in biopharmaceuticals. As part of the "21st Century Cures" initiative, Congress is reviewing the policy mechanisms designed to accelerate the discovery, development, and delivery of new treatments. Debate continues about how best to balance patent and intellectual property incentives to encourage innovation, on the one hand, and generic utilization and price competition, on the other hand. We review the current framework for accomplishing these dual objectives and the important role of patents and regulatory exclusivity (together, the patent-based system), given the lengthy, costly, and risky biopharmaceutical research and development process. We summarize existing targeted incentives, such as for orphan drugs and neglected diseases, and we consider the pros and cons of proposed voluntary or mandatory alternatives to the patent-based system, such as prizes and government research and development contracting. We conclude that patents and regulatory exclusivity provisions are likely to remain the core approach to providing incentives for biopharmaceutical research and development. However, prizes and other voluntary supplements could play a useful role in addressing unmet needs and gaps in specific circumstances.
dc.language eng
dc.relation.ispartof Health Aff (Millwood)
dc.relation.isversionof 10.1377/hlthaff.2014.1047
dc.subject Biotechnology
dc.subject Legal/Regulatory Issues
dc.subject Pharmaceuticals
dc.subject Awards and Prizes
dc.subject Biomedical Research
dc.subject Biopharmaceutics
dc.subject Drug Approval
dc.subject Drug Industry
dc.subject Humans
dc.subject Intellectual Property
dc.subject Neglected Diseases
dc.subject Orphan Drug Production
dc.subject Patents as Topic
dc.subject Pediatrics
dc.subject Reimbursement, Incentive
dc.subject Therapeutic Equivalency
dc.title The roles of patents and research and development incentives in biopharmaceutical innovation.
dc.type Journal article
pubs.author-url http://www.ncbi.nlm.nih.gov/pubmed/25646111
pubs.begin-page 302
pubs.end-page 310
pubs.issue 2
pubs.organisational-group Duke
pubs.organisational-group Economics
pubs.organisational-group Trinity College of Arts & Sciences
pubs.publication-status Published
pubs.volume 34
dc.identifier.eissn 1544-5208


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record