Hemorrhagic Herpes Simplex Virus Type 1 Nephritis: An Unusual Cause of Acute Allograft Dysfunction.
Abstract
Interstitial nephritis due to viruses is well-described after solid organ transplantation.
Viruses implicated include cytomegalovirus; BK polyomavirus; Epstein-Barr virus; and,
less commonly, adenovirus. We describe a rare case of hemorrhagic allograft nephritis
due to herpes simplex virus type 1 at 10 days after living donor kidney transplantation.
The patient had a favorable outcome with intravenous acyclovir and reduction of immunosuppression.
Type
Journal articleSubject
clinical research/practicedonors and donation
infection and infectious agents
infectious disease
kidney disease: infectious
kidney transplantation/nephrology
kidney transplantation: living donor
viral
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https://hdl.handle.net/10161/13102Published Version (Please cite this version)
10.1111/ajt.14022Publication Info
(2017). Hemorrhagic Herpes Simplex Virus Type 1 Nephritis: An Unusual Cause of Acute Allograft
Dysfunction. Am J Transplant, 17(1). pp. 287-291. 10.1111/ajt.14022. Retrieved from https://hdl.handle.net/10161/13102.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Barbara Dudley Alexander
Professor of Medicine
Clinical research related to infectious complications of solid organ and bone marrow
transplantation, with a particular interest in the treatment and rapid diagnosis of
fungal disease. Training the next generation of Transplant Infectious Disease Physicians
is a special focus of mine as the Principal Investigator of our Interdisciplinary
T32 Training Program funded the NIH.
John V Duronville
Assistant Professor of Medicine
Marion Hemmersbach Miller
House Staff
Nancy Gail Henshaw
Assistant Professor of Pathology
RESEARCH ABSTRACT Morphology and pathogenesis of Pneumocystis carinii, rapid viral
diagnosis, particularly in the immunocompromised host. Most of my research efforts
are of an applied nature which involves adapting new methods of rapid viral diagnosis
and testing those newer approaches against standard virological procedures. Validated
new tests are incorporated into the standard work-up of appropriate virological specimens.
Ultimately the expanded offerings result in a
David Noble Howell
Professor of Pathology
A major focus of both my clinical practice and investigative work is the diagnosis
and treatment of disorders affecting solid-organ transplant recipients, particularly
infectious complications. For the past 15 years, I have served as the primary pathologist
for one of the largest lung transplant programs in the world; in the process contributing
to over 20 peer-reviewed publications on complications of lung transplantation, including
infections, gastroesophageal reflux, tumors, and antibod
Sara Elizabeth Miller
Professor in Pathology
Our laboratory specializes in two areas, infectious diseases, particularlyviral diseases,
and ultrastructure-function relationships. Electronmicroscopy (EM) is the focus of
the investigative techniques and includes preparative methods such as negative staining,
thin sectioning, ultracryomicrotomy and immunolabeling of acrylic and frozen sections.
We are especially interested in methods for diagnosing viral illnesses by EM, and
are involved in developing better, more sensitive and fa
John Keith Roberts
Associate Professor of Medicine
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