Prevalence of renal anomalies after urinary tract infections in hospitalized infants less than 2 months of age.
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OBJECTIVE: Our aim was to determine the incidence of anatomical abnormalities after a urinary tract infection (UTI) in infants <2 months of age hospitalized in the neonatal intensive care unit (NICU). STUDY DESIGN: This was a retrospective, single-center cohort study of infants <2 months of age in the NICU with a UTI and documented renal imaging. RESULT: We identified 141 infants with UTIs. The mean gestational age and birth weight were 28 weeks and 1254 g, respectively. The most commonly identified pathogen was coagulase-negative Staphylococcus (28%, 44 of 156). A major abnormality was found on at least one imaging study for 4% (5 of 118) of infants. Major abnormalities were noted on 4% (5 of 114) of renal ultrasounds and 2% (2 of 82) of voiding cystourethrography examinations. CONCLUSION: Among infants in the NICU <2 months of age at the time of a UTI, the prevalence of major anatomical abnormalities is <5%.
SubjectAcademic Medical Centers
Intensive Care Units, Neonatal
Urinary Tract Infections
Published Version (Please cite this version)10.1038/jp.2009.147
Publication InfoAlexander, BD; Benjamin, Daniel Kelly; Cotten, CM; Moran, Cassandra; Nowell, L; Seed, Patrick C; ... Wiener, JS (2010). Prevalence of renal anomalies after urinary tract infections in hospitalized infants less than 2 months of age. J Perinatol, 30(4). pp. 281-285. 10.1038/jp.2009.147. Retrieved from http://hdl.handle.net/10161/13144.
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Assistant Professor of Anesthesiology
Associate Professor of Pediatrics
We are studying human microbial ecology and the molecular basis for different bacterial infections that are of relevance to both children and adults. Summaries of the research areas are described below: 1. THE MOLECULAR BASIS FOR VIRULENCE OF UROPATHOGENIC ESCHERICHIA COLI AND URINARY TRACT INFECTIONS. Uropathogenic Escherichia coli (UPEC) is the leading cause of community-acquired urinary tract infections (UTIs). Over 100 million UTIs occur annually throughout the world inclu
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