Show simple item record

A current perspective on stereotactic body radiation therapy for pancreatic cancer.

dc.contributor.author Hong, JC
dc.contributor.author Czito, BG
dc.contributor.author Willett, CG
dc.contributor.author Palta, M
dc.coverage.spatial New Zealand
dc.date.accessioned 2016-12-16T02:41:29Z
dc.date.issued 2016
dc.identifier http://www.ncbi.nlm.nih.gov/pubmed/27826200
dc.identifier ott-9-6733
dc.identifier.uri http://hdl.handle.net/10161/13277
dc.description.abstract Pancreatic cancer is a formidable malignancy with poor outcomes. The majority of patients are unable to undergo resection, which remains the only potentially curative treatment option. The management of locally advanced (unresectable) pancreatic cancer is controversial; however, treatment with either chemotherapy or chemoradiation is associated with high rates of local tumor progression and metastases development, resulting in low survival rates. An emerging local modality is stereotactic body radiation therapy (SBRT), which uses image-guided, conformal, high-dose radiation. SBRT has demonstrated promising local control rates and resultant quality of life with acceptable rates of toxicity. Over the past decade, increasing clinical experience and data have supported SBRT as a local treatment modality. Nevertheless, additional research is required to further evaluate the role of SBRT and improve upon the persistently poor outcomes associated with pancreatic cancer. This review discusses the existing clinical experience and technical implementation of SBRT for pancreatic cancer and highlights the directions for ongoing and future studies.
dc.language eng
dc.relation.ispartof Onco Targets Ther
dc.relation.isversionof 10.2147/OTT.S99826
dc.subject SBRT
dc.subject pancreatic cancer
dc.subject radiation therapy
dc.subject stereotactic body radiation therapy
dc.title A current perspective on stereotactic body radiation therapy for pancreatic cancer.
dc.type Journal article
pubs.author-url http://www.ncbi.nlm.nih.gov/pubmed/27826200
pubs.begin-page 6733
pubs.end-page 6739
pubs.organisational-group Clinical Science Departments
pubs.organisational-group Duke
pubs.organisational-group Duke Cancer Institute
pubs.organisational-group Institutes and Centers
pubs.organisational-group Radiation Oncology
pubs.organisational-group School of Medicine
pubs.organisational-group Staff
pubs.publication-status Published online
pubs.volume 9


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record