Relationship of trauma symptoms to amygdala-based functional brain changes in adolescents.
Repository Usage Stats
In this pilot study, amygdala connectivity related to trauma symptoms was explored using resting-state functional magnetic resonance imaging (R-fMRI) in 23 healthy adolescents ages 13-17 years with no psychiatric diagnoses. Adolescents completed a self-report trauma symptom checklist and a R-fMRI scan. We examined the relationship of trauma symptoms to resting-state functional connectivity of the amygdala. Increasing self-report of trauma symptoms by adolescents was associated with increasing functional connectivity with the right amygdala and a local limbic cluster and decreasing functional connectivity with the amygdala and a long-range frontoparietal cluster to the left amygdala, which can be a hallmark of immaturity. These pilot findings in adolescents provide preliminary evidence that even mild trauma symptoms can be linked to the configuration of brain networks associated with the amygdala.
Magnetic Resonance Imaging
Psychiatric Status Rating Scales
Stress Disorders, Post-Traumatic
Published Version (Please cite this version)10.1002/jts.21873
Publication InfoBrown, S; Castellanos, FX; Colcombe, SJ; Leventhal, B; Mennes, M; Milham, MP; & Nooner, Kate B (2013). Relationship of trauma symptoms to amygdala-based functional brain changes in adolescents. J Trauma Stress, 26(6). pp. 784-787. 10.1002/jts.21873. Retrieved from http://hdl.handle.net/10161/13514.
This is constructed from limited available data and may be imprecise. To cite this article, please review & use the official citation provided by the journal.
More InfoShow full item record
Adjunct Assistant Professor in the Department of Psychiatry and Behavioral Sciences
Dr. Kate Brody Nooner has NIH-funded research and collaborates with Dr. Michael De Bellis at Duke to conduct research as part of the National Consortium on Alcohol & Neurodevelopment in Adolescence. She is also a tenured Associate Professor in the Psychology Department at the University of North Carolina Wilmington.