Genetic mapping of brain plasticity across development in Williams syndrome: ERP markers of face and language processing.
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In Williams Syndrome (WS), a known genetic deletion results in atypical brain function with strengths in face and language processing. We examined how genetic influences on brain activity change with development. In three studies, event-related potentials (ERPs) from large samples of children, adolescents, and adults with the full genetic deletion for WS were compared to typically developing controls, and two adults with partial deletions for WS. Studies 1 and 2 identified ERP markers of brain plasticity in WS across development. Study 3 suggested that, in adults with partial deletions for WS, specific genes may be differentially implicated in face and language processing.
Published Version (Please cite this version)10.1080/87565641.2013.825617
Publication InfoMills, DL; Dai, L; Fishman, I; Yam, A; Appelbaum, Lawrence Gregory; St George, M; ... Korenberg, JR (2013). Genetic mapping of brain plasticity across development in Williams syndrome: ERP markers of face and language processing. Dev Neuropsychol, 38(8). pp. 613-642. 10.1080/87565641.2013.825617. Retrieved from http://hdl.handle.net/10161/13527.
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Associate Professor in Psychiatry and Behavioral Sciences
Greg Appelbaum is an Associate Professor in the Department of Psychiatry and Behavioral Sciences in the Duke University School of Medicine. He is a member of the Brain Stimulation Division of Psychiatry, where he directs the Human Performance Optimization lab (Opti Lab) and the Brain Stimulation Research Center As a member