A pilot randomized controlled trial with paroxetine for subthreshold PTSD in Operation Enduring Freedom/Operation Iraqi Freedom era veterans
Abstract
Subthreshold posttraumatic stress disorder (PTSD) is associated with increased risk
for suicidality, depression, and functional impairment. We thus conducted a small
(N=12) pilot randomized controlled trial (RCT) with paroxetine for subthreshold PTSD
in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) era veterans. Hospital
Anxiety and Depression Scale (HADS) scores improved by 30.4% in the paroxetine group.
Paroxetine may have promise for subthreshold PTSD.
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https://hdl.handle.net/10161/13846Published Version (Please cite this version)
10.1016/j.psychres.2012.11.008Publication Info
(2012). A pilot randomized controlled trial with paroxetine for subthreshold PTSD in Operation
Enduring Freedom/Operation Iraqi Freedom era veterans. Psychiatry Research. 10.1016/j.psychres.2012.11.008. Retrieved from https://hdl.handle.net/10161/13846.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Daniel William Bradford
Professor of Psychiatry and Behavioral Sciences
Dr. Bradford's clinical and administrative work, research, and teaching is all in
the area of mental health services for individuals with serious mental illnesses,
particularly psychotic disorders. Since 2012, he has served as the National Director
of Intensive Community Psychosocial Rehabilitation for the Department of Veterans
Affairs in the Office of Mental Health and Suicide Prevention. In this role, he is
responsible for policy development and oversight of over 170 assertive community
Jonathan R.T. Davidson
Professor Emeritus of Psychiatry and Behavioral Sciences
Currently, my research focuses upon the theoretical aspects of homeopathy and its
clinical utilization, as well as the broader field of alternative (complementary)
medicine. this is a field which has traditionally been overlooked as a legitimate
scientific discipline. Other areas of activity are as in the past, i.e., clinical
treatment, epidemiology, risk factors, pathogenesis of posttraumatic stress, social
phobia, other anxiety status, and depression. These are illustrated by recent pu
Jason David Kilts
Associate Professor in Psychiatry and Behavioral Sciences
Christine Elizabeth Marx
Professor of Psychiatry and Behavioral Sciences
Jennifer C. Naylor
Associate Professor in Psychiatry and Behavioral Sciences
Timothy J. Strauman
Professor of Psychology and Neuroscience
Professor Strauman's research focuses on the psychological and neurobiological processes
that enable self-regulation, conceptualized in terms of a cognitive/motivational perspective,
as well as the relation between self-regulation and affect. Particular areas of emphasis
include: (1) conceptualizing self-regulation in terms of brain/behavior motivational
systems; (2) the role of self-regulatory cognitive processes in vulnerability to depression
and other disorders; (3) the impact of tre
Jennifer Leigh Strauss
Associate Professor in Psychiatry and Behavioral Sciences
Steven Szabo
Assistant Professor of Psychiatry and Behavioral Sciences
Dr. Szabo received his undergraduate degree from the University of New Hampshire at
Plymouth and earned his PhD in Neurosciences at McGill University. He completed postdoctoral
training in Psychopharmacology at the University of Florida and in Mood and Anxiety
Disorders at NIMH before earning his medical degree from the Medical University of
the Americas. He completed his psychiatry residency training at Duke before joining
the faculty in 2013. As a substance abuse counselor
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