Geographic expansion of Lyme disease in Michigan, 2000-2014
Abstract
© The Author 2017.Background. Most Lyme disease cases in the Midwestern United States
are reported in Minnesota and Wisconsin. In recent years, however, a widening geographic
extent of Lyme disease has been noted with evidence of expansion eastwards into Michigan
and neighboring states with historically low incidence rates. Methods. We collected
confirmed and probable cases of Lyme disease from 2000 through 2014 from the Michigan
Department of Health and Human Services, entering them in a geographic information
system. We performed spatial focal cluster analyses to characterize Lyme disease expansion.
We compared the distribution of human cases with recent Ixodes scapularis tick distribution
studies. Results. Lyme disease cases in both the Upper and Lower Peninsulas of Michigan
expanded more than 5-fold over the study period. Although increases were seen throughout
the Upper Peninsula, the Lower Peninsula particularly expanded along the Indiana border
north along the eastern shore of Lake Michigan. Human cases corresponded to a simultaneous
expansion in established I scapularis tick populations. Conclusions. The geographic
distribution of Lyme disease cases significantly expanded in Michigan between 2000
and 2014, particularly northward along the Lake Michigan shore. If such dynamic trends
continue, Michigan-and possibly neighboring areas of Indiana, Ohio, and Ontario, Canada-can
expect a continued increase in Lyme disease cases.
Type
Journal articlePermalink
https://hdl.handle.net/10161/13950Published Version (Please cite this version)
10.1093/oid/ofw269Publication Info
Lantos, Paul M; Tsao, Jean; Nigrovic, Lise E; Auwaerter, Paul G; Fowler, Vance G;
Ruffin, Felicia; ... Hickling, Graham (2017). Geographic expansion of Lyme disease in Michigan, 2000-2014. Open Forum Infectious Diseases, 4(1). pp. 1-5. 10.1093/oid/ofw269. Retrieved from https://hdl.handle.net/10161/13950.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Vance Garrison Fowler Jr.
Florence McAlister Distinguished Professor of Medicine
Determinants of Outcome in Patients with Staphylococcus aureus Bacteremia Antibacterial
ResistancePathogenesis of Bacterial Infections Tropical medicine/International Health
Paul Michael Lantos
Professor of Medicine
I am interested in the spatial epidemiology of infectious diseases. My research utilizes
geographic information systems (GIS) and geostatistical analyses to understand the
spatial and spatiotemporal distribution of diseases, and their relationship with environmental
and demographic factors. I currently have active studies evaluating the spatial distribution
of numerous domestic and international infectious diseases, including SARS-CoV-2 (COVID-19),
cytomegalovirus, influenza, and Lyme disease. A
Felicia Ruffin
Research Program Leader, Tier 1
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