Outcome of Hematopoietic Cell Transplantation for DNA-Double Strand Breakage Repair Disorders.
DNA Ligase 4 deficiency
DNA repair disorders
Hematopoietic stem cell transplantation
Nijmegen Breakage syndrome
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Myeloablative transplantation using either cord blood or bone marrow leads to immune recovery, high long-term donor chimerism and excellent survival in chronic granulomatous disease. Tewari, Priti; Martin, Paul L; Mendizabal, Adam; Parikh, Suhag H; Page, Kristin M; Driscoll, Timothy A; Malech, Harry L; ... (9 authors) (Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012-09)The curative potential of hematopoietic stem cell transplantation in patients with chronic granulomatous disease depends on availability of a suitable donor, successful donor engraftment, and maintenance of long-term donor ...
Yang, Jun; Erdmann, Detlev; Chang, JC; Komatsu, Issei; Zhang, YiXin; Wang, DanRu; Hodavance, Michael S; ... (11 authors) (Plast Reconstr Surg, 2010-07)BACKGROUND: Some of the 600,000 patients with solid organ allotransplants need reconstruction with a composite tissue allotransplant, such as the hand, abdominal wall, or face. The aim of this study was to develop a rat ...
A novel reduced-intensity conditioning regimen for unrelated umbilical cord blood transplantation in children with nonmalignant diseases. Parikh, Suhag H; Mendizabal, Adam; Benjamin, Cara L; Komanduri, Krishna V; Antony, Jeyaraj; Petrovic, Aleksandra; Hale, Gregory; ... (15 authors) (Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2014-03)Reduced-intensity conditioning (RIC) regimens have the potential to decrease transplantation-related morbidity and mortality. However, engraftment failure has been prohibitively high after RIC unrelated umbilical cord blood ...