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Transient compartmentalization of simian immunodeficiency virus variants in the breast milk of african green monkeys.
dc.contributor.author | Ho, Carrie | |
dc.contributor.author | Wu, Steven | |
dc.contributor.author | Amos, Joshua D | |
dc.contributor.author | Colvin, Lisa | |
dc.contributor.author | Smith, Shannon D | |
dc.contributor.author | Wilks, Andrew B | |
dc.contributor.author | Demarco, C Todd | |
dc.contributor.author | Brinkley, Christie | |
dc.contributor.author | Denny, Thomas N | |
dc.contributor.author | Schmitz, Joern E | |
dc.contributor.author | Rodrigo, Allen G | |
dc.contributor.author | Permar, Sallie R | |
dc.coverage.spatial | United States | |
dc.date.accessioned | 2017-06-01T20:18:45Z | |
dc.date.available | 2017-06-01T20:18:45Z | |
dc.date.issued | 2013-10 | |
dc.identifier | https://www.ncbi.nlm.nih.gov/pubmed/23926337 | |
dc.identifier | JVI.01643-13 | |
dc.identifier.uri | https://hdl.handle.net/10161/14723 | |
dc.description.abstract | Natural hosts of simian immunodeficiency virus (SIV), African green monkeys (AGMs), rarely transmit SIV via breast-feeding. In order to examine the genetic diversity of breast milk SIV variants in this limited-transmission setting, we performed phylogenetic analysis on envelope sequences of milk and plasma SIV variants of AGMs. Low-diversity milk virus populations were compartmentalized from that in plasma. However, this compartmentalization was transient, as the milk virus lineages did not persist longitudinally. | |
dc.language | eng | |
dc.publisher | American Society for Microbiology | |
dc.relation.ispartof | J Virol | |
dc.relation.isversionof | 10.1128/JVI.01643-13 | |
dc.subject | Animals | |
dc.subject | Cercopithecus aethiops | |
dc.subject | Cluster Analysis | |
dc.subject | Female | |
dc.subject | Gene Products, env | |
dc.subject | Genetic Variation | |
dc.subject | Milk, Human | |
dc.subject | Phylogeny | |
dc.subject | Plasma | |
dc.subject | Sequence Analysis, DNA | |
dc.subject | Simian Acquired Immunodeficiency Syndrome | |
dc.subject | Simian Immunodeficiency Virus | |
dc.title | Transient compartmentalization of simian immunodeficiency virus variants in the breast milk of african green monkeys. | |
dc.type | Journal article | |
duke.contributor.id | Denny, Thomas N|0400543 | |
duke.contributor.id | Rodrigo, Allen G|0523698 | |
duke.contributor.id | Permar, Sallie R|0554303 | |
pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/23926337 | |
pubs.begin-page | 11292 | |
pubs.end-page | 11299 | |
pubs.issue | 20 | |
pubs.organisational-group | Basic Science Departments | |
pubs.organisational-group | Biology | |
pubs.organisational-group | Clinical Science Departments | |
pubs.organisational-group | Duke | |
pubs.organisational-group | Duke Human Vaccine Institute | |
pubs.organisational-group | Immunology | |
pubs.organisational-group | Institutes and Centers | |
pubs.organisational-group | Medicine | |
pubs.organisational-group | Medicine, Duke Human Vaccine Institute | |
pubs.organisational-group | Molecular Genetics and Microbiology | |
pubs.organisational-group | Pediatrics | |
pubs.organisational-group | Pediatrics, Infectious Diseases | |
pubs.organisational-group | School of Medicine | |
pubs.organisational-group | Trinity College of Arts & Sciences | |
pubs.publication-status | Published | |
pubs.volume | 87 | |
dc.identifier.eissn | 1098-5514 |
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