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The TALKS study to improve communication, logistical, and financial barriers to live donor kidney transplantation in African Americans: protocol of a randomized clinical trial.

dc.contributor.author Boulware, Ebony
dc.contributor.author Darrell, L
dc.contributor.author Ellis, M
dc.contributor.author Ephraim, Patti L
dc.contributor.author Falkovic, Margaret
dc.contributor.author Hill-Briggs, F
dc.contributor.author Kaiser, M
dc.contributor.author Lebov, JF
dc.contributor.author Pounds, Iris A
dc.contributor.author Rabb, H
dc.contributor.author Segev, D
dc.contributor.author Strigo, TS
dc.contributor.author Sudan, Debra L
dc.contributor.author Wang, N-Y
dc.coverage.spatial England
dc.date.accessioned 2017-08-02T02:08:00Z
dc.date.available 2017-08-02T02:08:00Z
dc.date.issued 2015-10-09
dc.identifier https://www.ncbi.nlm.nih.gov/pubmed/26452366
dc.identifier 10.1186/s12882-015-0153-y
dc.identifier.uri http://hdl.handle.net/10161/15164
dc.description.abstract BACKGROUND: Live donor kidney transplantation (LDKT), an optimal therapy for many patients with end-stage kidney disease, is underutilized, particularly by African Americans. Potential recipient difficulties initiating and sustaining conversations about LDKT, identifying willing and medically eligible donors, and potential donors' logistical and financial hurdles have been cited as potential contributors to race disparities in LDKT. Few interventions specifically targeting these factors have been tested. METHODS/DESIGN: We report the protocol of the Talking about Living Kidney Donation Support (TALKS) study, a study designed to evaluate the effectiveness of behavioral, educational and financial assistance interventions to improve access to LDKT among African Americans on the deceased donor kidney transplant recipient waiting list. We adapted a previously tested educational and social worker intervention shown to improve consideration and pursuit of LDKT among patients and their family members for its use among patients on the kidney transplant waiting list. We also developed a financial assistance intervention to help potential donors overcome logistical and financial challenges they might face during the pursuit of live kidney donation. We will evaluate the effectiveness of these interventions by conducting a randomized controlled trial in which patients on the deceased donor waiting list receive 1) usual care while on the transplant waiting list, 2) the educational and social worker intervention, or 3) the educational and social worker intervention plus the option of participating in the financial assistance program. The primary outcome of the randomized controlled trial will measure potential recipients' live kidney donor activation (a composite rate of live donor inquiries, completed new live donor evaluations, or live kidney donation) at 1 year. DISCUSSION: The TALKS study will rigorously assess the effectiveness of promising interventions to reduce race disparities in LDKT. TRIAL REGISTRATION: NCT02369354.
dc.language eng
dc.relation.ispartof BMC Nephrol
dc.relation.isversionof 10.1186/s12882-015-0153-y
dc.subject Adolescent
dc.subject Adult
dc.subject African Americans
dc.subject Aged
dc.subject Aged, 80 and over
dc.subject Communication Barriers
dc.subject Donor Selection
dc.subject Financial Support
dc.subject Health Knowledge, Attitudes, Practice
dc.subject Healthcare Disparities
dc.subject Humans
dc.subject Kidney Transplantation
dc.subject Living Donors
dc.subject Middle Aged
dc.subject Patient Education as Topic
dc.subject Research Design
dc.subject Social Work
dc.subject Tissue and Organ Procurement
dc.subject Young Adult
dc.title The TALKS study to improve communication, logistical, and financial barriers to live donor kidney transplantation in African Americans: protocol of a randomized clinical trial.
dc.type Journal article
pubs.author-url https://www.ncbi.nlm.nih.gov/pubmed/26452366
pubs.begin-page 160
pubs.organisational-group Clinical Science Departments
pubs.organisational-group Community and Family Medicine
pubs.organisational-group Duke
pubs.organisational-group Medicine
pubs.organisational-group Medicine, General Internal Medicine
pubs.organisational-group Medicine, Nephrology
pubs.organisational-group Pediatrics
pubs.organisational-group School of Medicine
pubs.organisational-group Staff
pubs.organisational-group Surgery
pubs.organisational-group Surgery, Abdominal Transplant Surgery
pubs.publication-status Published online
pubs.volume 16
dc.identifier.eissn 1471-2369


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