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Quantifying the utility of taking pills for preventing adverse health outcomes: a cross-sectional survey.

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Date
2015-05-11
Authors
Hutchins, Robert
Pignone, Michael P
Sheridan, Stacey L
Viera, Anthony J
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Abstract
OBJECTIVES: The utility value attributed to taking pills for prevention can have a major effect on the cost-effectiveness of interventions, but few published studies have systematically quantified this value. We sought to quantify the utility value of taking pills used for prevention of cardiovascular disease (CVD). DESIGN: Cross-sectional survey. SETTING: Central North Carolina. PARTICIPANTS: 708 healthcare employees aged 18 years and older. PRIMARY AND SECONDARY OUTCOMES: Utility values for taking 1 pill/day, assessed using time trade-off, modified standard gamble and willingness-to-pay methods. RESULTS: Mean age of respondents was 43 years (19-74). The majority of the respondents were female (83%) and Caucasian (80%). Most (80%) took at least 2 pills/day. Mean utility values for taking 1 pill/day using the time trade-off method were: 0.9972 (95% CI 0.9962 to 0.9980). Values derived from the standard gamble and willingness-to-pay methods were 0.9967 (0.9954 to 0.9979) and 0.9989 (95% CI 0.9986 to 0.9991), respectively. Utility values varied little across characteristics such as age, sex, race, education level or number of pills taken per day. CONCLUSIONS: The utility value of taking pills daily in order to prevent an adverse CVD health outcome is approximately 0.997.
Type
Journal article
Subject
cost-effectiveness
medical decision making
utility analysis
Adult
Aged
Attitude to Health
Cardiovascular Agents
Cardiovascular Diseases
Cross-Sectional Studies
Drug Administration Schedule
Female
Humans
Male
Middle Aged
North Carolina
Patient Compliance
Pharmaceutical Preparations
Preventive Medicine
Quality of Life
Young Adult
Permalink
https://hdl.handle.net/10161/15925
Published Version (Please cite this version)
10.1136/bmjopen-2014-006505
Publication Info
Hutchins, Robert; Pignone, Michael P; Sheridan, Stacey L; & Viera, Anthony J (2015). Quantifying the utility of taking pills for preventing adverse health outcomes: a cross-sectional survey. BMJ Open, 5(5). pp. e006505. 10.1136/bmjopen-2014-006505. Retrieved from https://hdl.handle.net/10161/15925.
This is constructed from limited available data and may be imprecise. To cite this article, please review & use the official citation provided by the journal.
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Scholars@Duke

Robert Preston Hutchins

Consulting Associate in the Department of Medicine
Viera

Anthony Joseph Viera

Professor of Family Medicine and Community Health
My major area of research is cardiovascular disease prevention. I am particularly interested in improving detection and control of hypertension. Since assessment of blood pressure begins with measurement, my studies often include out-of-office BP measurement techniques including 24-hour ambulatory BP monitoring and home BP monitoring. I am also interested in obesity prevention, and in another line of research am examining the effectiveness of food labeling policies (such as calorie-l
Alphabetical list of authors with Scholars@Duke profiles.
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