dc.contributor.author |
Marini, John J |
|
dc.contributor.author |
De Backer, Daniel |
|
dc.contributor.author |
Ince, Can |
|
dc.contributor.author |
Singer, Mervyn |
|
dc.contributor.author |
Van Haren, Frank |
|
dc.contributor.author |
Westphal, Martin |
|
dc.contributor.author |
Wischmeyer, Paul |
|
dc.coverage.spatial |
England |
|
dc.date.accessioned |
2018-01-17T18:21:47Z |
|
dc.date.available |
2018-01-17T18:21:47Z |
|
dc.date.issued |
2017-12-28 |
|
dc.identifier |
https://www.ncbi.nlm.nih.gov/pubmed/29297400 |
|
dc.identifier |
10.1186/s13054-017-1904-x |
|
dc.identifier.uri |
https://hdl.handle.net/10161/15998 |
|
dc.description.abstract |
With imprecise definitions, inexact measurement tools, and flawed study execution,
our clinical science often lags behind bedside experience and simply documents what
appear to be the apparent faults or validity of ongoing practices. These impressions
are later confirmed, modified, or overturned by the results of the next trial. On
the other hand, insights that stem from the intuitions of experienced clinicians,
scientists and educators-while often neglected-help place current thinking into proper
perspective and occasionally point the way toward formulating novel hypotheses that
direct future research. Both streams of information and opinion contribute to progress.
In this paper we present a wide-ranging set of unproven 'out of the mainstream' ideas
of our FCCM faculty, each with a defensible rationale and holding clear implications
for altering bedside management. Each proposition was designed deliberately to be
provocative so as to raise awareness, stimulate new thinking and initiate lively dialog.
|
|
dc.language |
eng |
|
dc.publisher |
Springer Science and Business Media LLC |
|
dc.relation.ispartof |
Crit Care |
|
dc.relation.isversionof |
10.1186/s13054-017-1904-x |
|
dc.subject |
Adaptive clinical trials |
|
dc.subject |
Melatonin |
|
dc.subject |
Metabolic monitoring |
|
dc.subject |
Microcirculation |
|
dc.subject |
Personalized medicine |
|
dc.subject |
Resuscitation |
|
dc.subject |
Sepsis |
|
dc.subject |
Shock |
|
dc.subject |
Ventilator-induced lung injury |
|
dc.title |
Seven unconfirmed ideas to improve future ICU practice. |
|
dc.type |
Journal article |
|
duke.contributor.id |
Wischmeyer, Paul|0721619 |
|
pubs.author-url |
https://www.ncbi.nlm.nih.gov/pubmed/29297400 |
|
pubs.begin-page |
315 |
|
pubs.issue |
Suppl 3 |
|
pubs.organisational-group |
Anesthesiology |
|
pubs.organisational-group |
Anesthesiology, Critical Care Medicine |
|
pubs.organisational-group |
Clinical Science Departments |
|
pubs.organisational-group |
Duke |
|
pubs.organisational-group |
Duke Clinical Research Institute |
|
pubs.organisational-group |
Institutes and Centers |
|
pubs.organisational-group |
School of Medicine |
|
pubs.publication-status |
Published online |
|
pubs.volume |
21 |
|
dc.identifier.eissn |
1466-609X |
|