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Heart failure in sub-Saharan Africa.

dc.contributor.author Barasa, FA
dc.contributor.author Bloomfield, Gerald
dc.contributor.author Doll, JA
dc.contributor.author Velazquez, Eric J
dc.coverage.spatial United Arab Emirates
dc.date.accessioned 2018-02-13T18:50:33Z
dc.date.available 2018-02-13T18:50:33Z
dc.date.issued 2013-05
dc.identifier https://www.ncbi.nlm.nih.gov/pubmed/23597299
dc.identifier CCR-EPUB-20130415-5
dc.identifier.uri https://hdl.handle.net/10161/16080
dc.description.abstract The heart failure syndrome has been recognized as a significant contributor to cardiovascular disease burden in sub-Saharan African for many decades. Seminal knowledge regarding heart failure in the region came from case reports and case series of the early 20th century which identified infectious, nutritional and idiopathic causes as the most common. With increasing urbanization, changes in lifestyle habits, and ageing of the population, the spectrum of causes of HF has also expanded resulting in a significant burden of both communicable and non-communicable etiologies. Heart failure in sub-Saharan Africa is notable for the range of etiologies that concurrently exist as well as the healthcare environment marked by limited resources, weak national healthcare systems and a paucity of national level data on disease trends. With the recent publication of the first and largest multinational prospective registry of acute heart failure in sub-Saharan Africa, it is timely to review the state of knowledge to date and describe the myriad forms of heart failure in the region. This review discusses several forms of heart failure that are common in sub-Saharan Africa (e.g., rheumatic heart disease, hypertensive heart disease, pericardial disease, various dilated cardiomyopathies, HIV cardiomyopathy, hypertrophic cardiomyopathy, endomyocardial fibrosis, ischemic heart disease, cor pulmonale) and presents each form with regard to epidemiology, natural history, clinical characteristics, diagnostic considerations and therapies. Areas and approaches to fill the remaining gaps in knowledge are also offered herein highlighting the need for research that is driven by regional disease burden and needs.
dc.language eng
dc.relation.ispartof Curr Cardiol Rev
dc.subject Africa South of the Sahara
dc.subject Cardiomyopathies
dc.subject Causality
dc.subject Comorbidity
dc.subject Endomyocardial Fibrosis
dc.subject HIV Infections
dc.subject Heart Failure
dc.subject Humans
dc.subject Hypertension
dc.subject Myocardial Ischemia
dc.subject Pulmonary Heart Disease
dc.subject Rheumatic Heart Disease
dc.title Heart failure in sub-Saharan Africa.
dc.type Journal article
pubs.author-url https://www.ncbi.nlm.nih.gov/pubmed/23597299
pubs.begin-page 157
pubs.end-page 173
pubs.issue 2
pubs.organisational-group Clinical Science Departments
pubs.organisational-group Duke
pubs.organisational-group Duke Clinical Research Institute
pubs.organisational-group Duke Global Health Institute
pubs.organisational-group Institutes and Centers
pubs.organisational-group Institutes and Provost's Academic Units
pubs.organisational-group Medicine
pubs.organisational-group Medicine, Cardiology
pubs.organisational-group School of Medicine
pubs.organisational-group University Institutes and Centers
pubs.publication-status Published
pubs.volume 9
dc.identifier.eissn 1875-6557


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