A practical method of I-131 thyroid cancer therapy dose optimization using estimated effective renal clearance.
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In thyroid cancer patients with renal impairment or other complicating factors, it is important to maximize I-131 therapy efficacy while minimizing bone marrow and lung damage. We developed a web-based calculator based on a modified Benua and Leeper method to calculate the maximum I-131 dose to reduce the risk of these toxicities, based on the effective renal clearance of I-123 as measured from two whole-body I-123 scans, performed at 0 and 24 h post-administration.
Published Version (Please cite this version)10.1177/2050313X17745203
Publication InfoBorges-Neto, Salvador; Howard, Brandon A; James, OG; Pagnanelli, RA; Perkins, JM; & Reiman, Robert E Jr (2017). A practical method of I-131 thyroid cancer therapy dose optimization using estimated effective renal clearance. SAGE Open Med Case Rep, 5. 10.1177/2050313X17745203. Retrieved from https://hdl.handle.net/10161/16135.
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Professor of Radiology
Expertise: 1. Diagnostic and Prognostic Utility of Cardiovascular Nuclear Medicine in Heart Disease. 2. The Role of Cardiac PET/CT in Cardiac Sarcoidosis and Ischemic Heart Disease. 3. The Role of Nuclear Cardiology in Diagnosis and Management of Amyloidosis. 4. Left Ventricular Dyssynchrony Evaluation by GSPECT. I am a Professor of Radiology (Nuclear Medicine) and Internal Medicine at Duke University Medical Center. I also serve as
Associate Professor of Radiology
Dr. Reiman is diplomate of the American Board of Nuclear Medicine, and is the Associate Director the Radiation Safety Division of Duke's Occupational and Environmental Safety Office. He is on the faculty the Department of Radiology and a member of the Faculty of the Duke Medical Physics Graduate Program. He coordinates the patient care activities of the Duke Radiation Safety Division and participates in the teaching of radiology residents, and cardiology fellows and m
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