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AIDS‐associated Cryptococcus neoformans and Penicillium marneffei coinfection: a therapeutic dilemma in resource‐limited settings.
Abstract
AIDS‐associated Cryptococcus neoformans and Penicillium marneffei coinfection
has not been adequately studied and poses unique therapeutic challenges in resource‐limited
settings. Itraconazole poorly penetrates the central nervous system, whereas fluconazole
has poor activity against P. marneffei. We prospectively report management of 1 patient
and retrospectively review 7 coinfection cases from Vietnam.
Type
Journal articleSubject
AIDS-Related Opportunistic InfectionsAdult
Antifungal Agents
Cryptococcus neoformans
Developing Countries
Diagnosis, Differential
Fluconazole
Humans
Itraconazole
Male
Mycoses
Penicillium
Prospective Studies
Retrospective Studies
Vietnam
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https://hdl.handle.net/10161/16198Published Version (Please cite this version)
10.1086/656685Publication Info
Le, Thuy; Hong Chau, Tran Thi; Kim Cuc, Ngo Thi; Si Lam, Pham; Manh Sieu, Tran Phu;
Shikuma, Cecilia M; & Day, Jeremy N (2010). AIDS‐associated Cryptococcus neoformans and Penicillium marneffei coinfection: a therapeutic
dilemma in resource‐limited settings. Clin Infect Dis, 51(9). pp. e65-e68. 10.1086/656685. Retrieved from https://hdl.handle.net/10161/16198.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Thuy Le
Associate Professor of Medicine

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