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An Update on Surgical versus Expectant Management of Ovarian Endometriomas in Infertile Women.
Abstract
Ovarian endometriomas are a common manifestation of endometriosis that can represent
a more severe stage of the disease. There is much debate over the treatment of these
cysts in infertile women, particularly before use of assisted reproductive technologies.
Evidence exists that supports surgical excision of ovarian endometriomas, as well
as evidence that cautions against surgical intervention. Certain factors need to be
examined closely before proceeding with surgery or continuing with expectant management.
These include the patient's symptoms, age, ovarian reserve, size and laterality of
the cyst, prior surgical treatment, and level of suspicion for malignancy. The most
recent evidence appears to suggest that certain patient profiles may benefit from
proceeding directly to in vitro fertilization (IVF). These include symptomatic infertile
patients, especially those that are older, those that have diminished ovarian reserve,
those that have bilateral endometriomas, or those that have had prior surgical treatment.
Although endometriomas can be detrimental to the ovarian reserve, surgical therapy
may further lower a woman's ovarian reserve. Nevertheless, the presence of an endometrioma
does not appear to adversely affect IVF outcomes, and surgical excision of endometriomas
does not appear to improve IVF outcomes. Regardless of treatment plan, infertile patients
with endometriomas must be counseled appropriately before choosing either treatment
path.
Type
Journal articleSubject
HumansOvarian Cysts
Endometriosis
Infertility, Female
Postoperative Complications
Pelvic Pain
Treatment Outcome
Ovariectomy
Incidence
Risk Factors
Evidence-Based Medicine
Causality
Comorbidity
Female
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https://hdl.handle.net/10161/17133Published Version (Please cite this version)
10.1155/2015/204792Publication Info
Keyhan, Sanaz; Hughes, Claude; Price, Thomas; & Muasher, Suheil (2015). An Update on Surgical versus Expectant Management of Ovarian Endometriomas in Infertile
Women. BioMed research international, 2015. 10.1155/2015/204792. Retrieved from https://hdl.handle.net/10161/17133.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Claude Lebernian Hughes Jr.
Consulting Professor of Obstetrics and Gynecology
Suheil Jamil Muasher
Professor Emeritus of Obstetrics and Gynecology
I currently hold the position of Director of Graduate Learning and Academic Development.
I am responsible for the education of the second year residents rotating in REI and
director of second year medical student rotation in REI. I give ten resident lectures
per year covering all the CREOG educational requirements. I also conduct case based
learning sessions for the medical students throughout the year (2 hours per week).
I conduct journal club sessions with t
Thomas Michael Price
Professor Emeritus of Obstetrics and Gynecology
Dr. Price is involved in both clinical and basic science research. The main focus
of the basic science molecular endocrinology laboratory is the study of novel sex
steroid receptors. Currently, the work focuses on a novel progesterone receptor that
localizes to the mitochondrion. Studies including RNAi in cell models and creation
of transgenic mice are ongoing to discover the function of this receptor. The overall
hypothesis is that progesterone modulates mitochondrial activity to meet the incre
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