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Radiographic Fusion Grade Does Not Impact Health-Related Quality of Life in the Absence of Instrumentation Failure for Patients Undergoing Posterior Instrumented Fusion for Adult Spinal Deformity
Abstract
© 2018 Background: Pseudarthrosis and rod fracture (RF) remain significant concerns
after fusion for adult spinal deformity (ASD). Although a radiographic system of fusion
grade has been proposed, the correlation between fusion grade and health-related quality
of life measures (HRQoL) is not known. Methods: In a retrospective review of a prospectively
collected clinical database, patients that underwent ≥5-level posterior instrumented
arthrodesis for ASD were evaluated. Fusion grade was determined on plain films using
the Lenke criteria. Patients were grouped as 1) complete fusion (grade I or II at
all levels), 2) incomplete fusion (grade 3 or 4 at any level), 3) rod fracture without
revision (RF), and 4) rod fracture with revision (RFR). Outcome measures were the
Oswestry Disability Index, Medical Outcomes Study 36-Item Short-Form Health Survey
Physical and Mental Component Summaries, Scoliosis Research Society-22r total, and
Lumbar Stiffness and Disability Index. Results: There were 205 (85%) patients who
achieved the minimum 2-year follow-up and were included. Complete fusion was achieved
in 115 patients (56.1%), 55% patients (26.8%) had incomplete fusion, and 35% patients
(17.1%) had RF. Of the 35 patients with RF, 19 (17.1%; 19/205) underwent revision
while 16 (7.8%; 16/205) had RF without revision. HRQoL measures were significantly
worse in the RFR group, whereas no significant differences were found between groups
1, 2, and 3. Conclusions: Radiographic fusion grade after ASD surgery did not significantly
impact HRQoL in the absence of RF. RFR was associated with significantly worse clinical
outcomes. Fusion grade may be less predictive of clinical outcomes than the occurrence
of RF.
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https://hdl.handle.net/10161/17576Published Version (Please cite this version)
10.1016/j.wneu.2018.04.127Publication Info
Ailon, Tamir; Hamilton, D Koho; Klineberg, Erik; Daniels, Alan H; Lafage, Virginie;
Bess, Shay; ... International Spine Study Group (2018). Radiographic Fusion Grade Does Not Impact Health-Related Quality of Life in the Absence
of Instrumentation Failure for Patients Undergoing Posterior Instrumented Fusion for
Adult Spinal Deformity. World Neurosurgery, 117. pp. e1-e7. 10.1016/j.wneu.2018.04.127. Retrieved from https://hdl.handle.net/10161/17576.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Christopher Ignatius Shaffrey
Professor of Orthopaedic Surgery
I have more than 25 years of experience treating patients of all ages with spinal
disorders. I have had an interest in the management of spinal disorders since starting
my medical education. I performed residencies in both orthopaedic surgery and neurosurgery
to gain a comprehensive understanding of the entire range of spinal disorders. My
goal has been to find innovative ways to manage the range of spinal conditions, straightforward
to complex. I have a focus on managing patients with complex s

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