Show simple item record

Outcomes of Operative Treatment for Adult Cervical Deformity: A Prospective Multicenter Assessment With 1-Year Follow-up.

dc.contributor.author Shaffrey, Christopher
dc.contributor.author Ailon, Tamir
dc.contributor.author Smith, Justin S
dc.contributor.author Kim, Han Jo
dc.contributor.author Mundis, Gregory
dc.contributor.author Gupta, Munish
dc.contributor.author Klineberg, Eric
dc.contributor.author Schwab, Frank
dc.contributor.author Lafage, Virginie
dc.contributor.author Lafage, Renaud
dc.contributor.author Passias, Peter
dc.contributor.author Protopsaltis, Themistocles
dc.contributor.author Neuman, Brian
dc.contributor.author Daniels, Alan
dc.contributor.author Scheer, Justin K
dc.contributor.author Soroceanu, Alex
dc.contributor.author Hart, Robert
dc.contributor.author Hostin, Rick
dc.contributor.author Burton, Douglas
dc.contributor.author Deviren, Vedat
dc.contributor.author Albert, Todd J
dc.contributor.author Riew, K Daniel
dc.contributor.author Bess, Shay
dc.contributor.author Ames, Christopher P
dc.date.accessioned 2018-11-07T21:09:41Z
dc.date.available 2018-11-07T21:09:41Z
dc.date.issued 2018-11
dc.identifier 4769324
dc.identifier.issn 0148-396X
dc.identifier.issn 1524-4040
dc.identifier.uri https://hdl.handle.net/10161/17638
dc.description.abstract BACKGROUND:Despite the potential for profound impact of adult cervical deformity (ACD) on function and health-related quality of life (HRQOL), there are few high-quality studies that assess outcomes of surgical treatment for these patients. OBJECTIVE:To determine the impact of surgical treatment for ACD on HRQOL. METHODS:We conducted a prospective cohort study of surgically treated ACD patients eligible for 1-yr follow-up. Baseline deformity characteristics, surgical parameters, and 1-yr HRQOL outcomes were assessed. RESULTS:Of 77 ACD patients, 55 (71%) had 1-yr follow-up (64% women, mean age of 62 yr, mean Charlson Comorbidity Index of 0.6, previous cervical surgery in 47%). Diagnoses included cervical sagittal imbalance (56%), cervical kyphosis (55%), proximal junctional kyphosis (7%) and coronal deformity (9%). Posterior fusion was performed in 85% (mean levels = 10), and anterior fusion was performed in 53% (mean levels = 5). Three-column osteotomy was performed in 24% of patients. One year following surgery, ACD patients had significant improvement in Neck Disability Index (50.5 to 38.0, P < .001), neck pain numeric rating scale score (6.9 to 4.3, P < .001), EuroQol 5 dimension (EQ-5D) index (0.51 to 0.66, P < .001), and EQ-5D subscores: mobility (1.9 to 1.7, P = .019), usual activities (2.2 to 1.9, P = .007), pain/discomfort (2.4 to 2.1, P < .001), anxiety/depression (1.8 to 1.5, P = .014). CONCLUSION:Based on a prospective multicenter series of ACD patients, surgical treatment provided significant improvement in multiple measures of pain and function, including Neck Disability Index, neck pain numeric rating scale score, and EQ-5D. Further follow-up will be necessary to assess the long-term durability of these improved outcomes.
dc.language eng
dc.relation.ispartof Neurosurgery
dc.relation.isversionof 10.1093/neuros/nyx574
dc.subject International Spine Study Group
dc.title Outcomes of Operative Treatment for Adult Cervical Deformity: A Prospective Multicenter Assessment With 1-Year Follow-up.
dc.type Journal article
dc.date.updated 2018-11-07T21:09:40Z
pubs.begin-page 1031
pubs.end-page 1039
pubs.issue 5
pubs.organisational-group School of Medicine
pubs.organisational-group Duke
pubs.organisational-group Orthopaedics
pubs.organisational-group Clinical Science Departments
pubs.organisational-group Neurosurgery
pubs.publication-status Accepted
pubs.volume 83


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record