Show simple item record

Retinal representation of the elementary visual signal.

dc.contributor.author Li, Peter H
dc.contributor.author Field, Greg D
dc.contributor.author Greschner, Martin
dc.contributor.author Ahn, Daniel
dc.contributor.author Gunning, Deborah E
dc.contributor.author Mathieson, Keith
dc.contributor.author Sher, Alexander
dc.contributor.author Litke, Alan M
dc.contributor.author Chichilnisky, EJ
dc.date.accessioned 2019-01-03T15:40:27Z
dc.date.available 2019-01-03T15:40:27Z
dc.date.issued 2014-01
dc.identifier S0896-6273(13)00995-1
dc.identifier.issn 0896-6273
dc.identifier.issn 1097-4199
dc.identifier.uri https://hdl.handle.net/10161/17867
dc.description.abstract The propagation of visual signals from individual cone photoreceptors through parallel neural circuits was examined in the primate retina. Targeted stimulation of individual cones was combined with simultaneous recording from multiple retinal ganglion cells of identified types. The visual signal initiated by an individual cone produced strong responses with different kinetics in three of the four numerically dominant ganglion cell types. The magnitude and kinetics of light responses in each ganglion cell varied nonlinearly with stimulus strength but in a manner that was independent of the cone of origin after accounting for the overall input strength of each cone. Based on this property of independence, the receptive field profile of an individual ganglion cell could be well estimated from responses to stimulation of each cone individually. Together, these findings provide a quantitative account of how elementary visual inputs form the ganglion cell receptive field.
dc.language eng
dc.publisher Elsevier BV
dc.relation.ispartof Neuron
dc.relation.isversionof 10.1016/j.neuron.2013.10.043
dc.subject Visual Pathways
dc.subject Retinal Ganglion Cells
dc.subject Retina
dc.subject Animals
dc.subject Macaca mulatta
dc.subject Photic Stimulation
dc.subject Action Potentials
dc.subject Visual Fields
dc.subject Retinal Cone Photoreceptor Cells
dc.subject In Vitro Techniques
dc.title Retinal representation of the elementary visual signal.
dc.type Journal article
duke.contributor.id Field, Greg D|0663656
dc.date.updated 2019-01-03T15:40:26Z
pubs.begin-page 130
pubs.end-page 139
pubs.issue 1
pubs.organisational-group School of Medicine
pubs.organisational-group Duke
pubs.organisational-group Biomedical Engineering
pubs.organisational-group Pratt School of Engineering
pubs.organisational-group Neurobiology
pubs.organisational-group Basic Science Departments
pubs.organisational-group Duke Institute for Brain Sciences
pubs.organisational-group University Institutes and Centers
pubs.organisational-group Institutes and Provost's Academic Units
pubs.publication-status Published
pubs.volume 81


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record