Show simple item record

Auditory signals evolve from hybrid- to eye-centered coordinates in the primate superior colliculus.

dc.contributor.author Groh, Jennifer
dc.contributor.author Lee, Jungah
dc.date.accessioned 2019-01-07T19:16:46Z
dc.date.available 2019-01-07T19:16:46Z
dc.date.issued 2012-07
dc.identifier jn.00706.2011
dc.identifier.issn 0022-3077
dc.identifier.issn 1522-1598
dc.identifier.uri https://hdl.handle.net/10161/17893
dc.description.abstract Visual and auditory spatial signals initially arise in different reference frames. It has been postulated that auditory signals are translated from a head-centered to an eye-centered frame of reference compatible with the visual spatial maps, but, to date, only various forms of hybrid reference frames for sound have been identified. Here, we show that the auditory representation of space in the superior colliculus involves a hybrid reference frame immediately after the sound onset but evolves to become predominantly eye centered, and more similar to the visual representation, by the time of a saccade to that sound. Specifically, during the first 500 ms after the sound onset, auditory response patterns (N = 103) were usually neither head nor eye centered: 64% of neurons showed such a hybrid pattern, whereas 29% were more eye centered and 8% were more head centered. This differed from the pattern observed for visual targets (N = 156): 86% were eye centered, <1% were head centered, and only 13% exhibited a hybrid of both reference frames. For auditory-evoked activity observed within 20 ms of the saccade (N = 154), the proportion of eye-centered response patterns increased to 69%, whereas the hybrid and head-centered response patterns dropped to 30% and <1%, respectively. This pattern approached, although did not quite reach, that observed for saccade-related activity for visual targets: 89% were eye centered, 11% were hybrid, and <1% were head centered (N = 162). The plainly eye-centered visual response patterns and predominantly eye-centered auditory motor response patterns lie in marked contrast to our previous study of the intraparietal cortex, where both visual and auditory sensory and motor-related activity used a predominantly hybrid reference frame (Mullette-Gillman et al. 2005, 2009). Our present findings indicate that auditory signals are ultimately translated into a reference frame roughly similar to that used for vision, but suggest that such signals might emerge only in motor areas responsible for directing gaze to visual and auditory stimuli.
dc.language eng
dc.publisher American Physiological Society
dc.relation.ispartof Journal of neurophysiology
dc.relation.isversionof 10.1152/jn.00706.2011
dc.subject Neurons
dc.subject Animals
dc.subject Macaca mulatta
dc.subject Acoustic Stimulation
dc.subject Analysis of Variance
dc.subject Photic Stimulation
dc.subject Sound Localization
dc.subject Space Perception
dc.subject Psychomotor Performance
dc.subject Action Potentials
dc.subject Head Movements
dc.subject Saccades
dc.subject Time Factors
dc.subject Female
dc.subject Male
dc.subject Statistics as Topic
dc.subject Superior Colliculi
dc.title Auditory signals evolve from hybrid- to eye-centered coordinates in the primate superior colliculus.
dc.type Journal article
dc.date.updated 2019-01-07T19:16:46Z
pubs.begin-page 227
pubs.end-page 242
pubs.issue 1
pubs.organisational-group Trinity College of Arts & Sciences
pubs.organisational-group Duke
pubs.organisational-group Psychology and Neuroscience
pubs.organisational-group Neurobiology
pubs.organisational-group Basic Science Departments
pubs.organisational-group School of Medicine
pubs.organisational-group Duke Institute for Brain Sciences
pubs.organisational-group University Institutes and Centers
pubs.organisational-group Institutes and Provost's Academic Units
pubs.organisational-group Center for Cognitive Neuroscience
pubs.publication-status Published
pubs.volume 108
duke.contributor.orcid Groh, Jennifer|0000-0002-6435-3935


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record