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Distribution of eye position information in the monkey inferior colliculus.

dc.contributor.author Bulkin, David A
dc.contributor.author Groh, Jennifer M
dc.date.accessioned 2019-01-07T19:17:33Z
dc.date.available 2019-01-07T19:17:33Z
dc.date.issued 2012-02
dc.identifier jn.00662.2011
dc.identifier.issn 0022-3077
dc.identifier.issn 1522-1598
dc.identifier.uri https://hdl.handle.net/10161/17894
dc.description.abstract The inferior colliculus (IC) is thought to have two main subdivisions, a central region that forms an important stop on the ascending auditory pathway and a surrounding shell region that may play a more modulatory role. In this study, we investigated whether eye position affects activity in both the central and shell regions. Accordingly, we mapped the location of eye position-sensitive neurons in six monkeys making spontaneous eye movements by sampling multiunit activity at regularly spaced intervals throughout the IC. We used a functional map based on auditory response patterns to estimate the anatomical location of recordings, in conjunction with structural MRI and histology. We found eye position-sensitive sites throughout the IC, including at 27% of sites in tonotopically organized recording penetrations (putatively the central nucleus). Recordings from surrounding tissue showed a larger proportion of sites indicating an influence of eye position (33-43%). When present, the magnitude of the change in activity due to eye position was often comparable to that seen for sound frequency. Our results indicate that the primary ascending auditory pathway is influenced by the position of the eyes. Because eye position is essential for visual-auditory integration, our findings suggest that computations underlying visual-auditory integration begin early in the ascending auditory pathway.
dc.language eng
dc.publisher American Physiological Society
dc.relation.ispartof Journal of neurophysiology
dc.relation.isversionof 10.1152/jn.00662.2011
dc.subject Auditory Pathways
dc.subject Animals
dc.subject Haplorhini
dc.subject Eye Movements
dc.subject Brain Mapping
dc.subject Sound Localization
dc.subject Female
dc.subject Male
dc.subject Inferior Colliculi
dc.title Distribution of eye position information in the monkey inferior colliculus.
dc.type Journal article
duke.contributor.id Groh, Jennifer M|0392251
dc.date.updated 2019-01-07T19:17:32Z
pubs.begin-page 785
pubs.end-page 795
pubs.issue 3
pubs.organisational-group Trinity College of Arts & Sciences
pubs.organisational-group Duke
pubs.organisational-group Psychology and Neuroscience
pubs.organisational-group Neurobiology
pubs.organisational-group Basic Science Departments
pubs.organisational-group School of Medicine
pubs.organisational-group Duke Institute for Brain Sciences
pubs.organisational-group University Institutes and Centers
pubs.organisational-group Institutes and Provost's Academic Units
pubs.organisational-group Center for Cognitive Neuroscience
pubs.publication-status Published
pubs.volume 107
duke.contributor.orcid Groh, Jennifer M|0000-0002-6435-3935


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