Transcatheter Valve Replacement for Right-sided Valve Disease in Congenital Heart Patients.
Abstract
Pulmonary and/or tricuspid valve dysfunction is common among individuals with congenital
heart disease, and surgical intervention often carries prohibitive risks. Transcatheter
valve replacement (TVR) of the right-sided cardiac valves has become a viable treatment
option over the past two decades, while continued technological development aims to
broaden its applicability to an even larger portion of those with repaired congenital
heart disease. To date, two transcatheter valves have been approved for use in patients
with dysfunctional right ventricular to pulmonary artery conduits as well as those
with failing pulmonic bioprosthetic valves, and are also used off-label in the "native"
RVOT and within surgically repaired/replaced but failing tricuspid valves. TVR has
demonstrated comparable safety and short-term outcomes to that of surgical valve replacement.
This article aims to review current available devices, focusing on their safety, efficacy
and on and off label usage, while briefly describing some of the emerging devices
and novel procedural techniques that will likely lead to significant expansion of
transcatheter treatment of right sided valve disease in the future.
Type
Journal articleSubject
Pulmonary ValveTricuspid Valve
Humans
Heart Defects, Congenital
Heart Valve Diseases
Treatment Outcome
Heart Valve Prosthesis Implantation
Heart Valve Prosthesis
Adult
Cardiac Catheterization
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https://hdl.handle.net/10161/17933Published Version (Please cite this version)
10.1016/j.pcad.2018.09.003Publication Info
Gales, Jordan; Krasuski, Richard A; & Fleming, Gregory A (2018). Transcatheter Valve Replacement for Right-sided Valve Disease in Congenital Heart
Patients. Progress in cardiovascular diseases, 61(3-4). pp. 347-359. 10.1016/j.pcad.2018.09.003. Retrieved from https://hdl.handle.net/10161/17933.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Gregory Allan Fleming
Professor of Pediatrics
Clinical interests include pediatric and adult congenital interventional cardiac catheterization
and treatment of infants and children with acquired and congenital heart disease and
adults with congenital heart disease Research interests include assessment and development
of interventional therapies for congenital heart disease, and perioperative management
of infants and children with congenital heart disease requiring surgery.
Richard Andrew Krasuski
Professor of Medicine
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