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Heart Transplantation and Mechanical Circulatory Support in Adults with Congenital Heart Disease.

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Date
2018-08-09
Authors
Serfas, John D
Patel, Priyesh A
Krasuski, Richard A
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Abstract
PURPOSE OF REVIEW:To assess current management strategies for advanced heart failure in adults with congenital heart disease, including heart transplantation and mechanical circulatory support. RECENT FINDINGS:Current data demonstrate that adults with CHD generally experience higher short-term mortality after heart transplantation and MCS implantation, but enjoy superior long-term survival. Such patients are nonetheless less likely to receive a transplant than non-ACHD peers due to a variety of factors, including lack of applicability of current listing criteria to HF in ACHD. MCS is underutilized in ACHD, but provides similar quality of life benefits for ACHD and non-ACHD patients alike. Heart failure in ACHD is complex and difficult to treat, and both heart transplantation and mechanical circulatory support are often challenging to implement in this patient population. However, long-term results are encouraging, and existing data supports increasing use of MCS and transplant earlier in their disease course. Multidisciplinary care is critical to success in these complex patients.
Type
Journal article
Subject
Adult congenital heart disease
Failing Fontan
Heart transplantation
LVAD
Mechanical circulatory support
Permalink
https://hdl.handle.net/10161/17940
Published Version (Please cite this version)
10.1007/s11886-018-1028-1
Publication Info
Serfas, John D; Patel, Priyesh A; & Krasuski, Richard A (2018). Heart Transplantation and Mechanical Circulatory Support in Adults with Congenital Heart Disease. Current cardiology reports, 20(10). pp. 81. 10.1007/s11886-018-1028-1. Retrieved from https://hdl.handle.net/10161/17940.
This is constructed from limited available data and may be imprecise. To cite this article, please review & use the official citation provided by the journal.
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Scholars@Duke

Krasuski

Richard Andrew Krasuski

Professor of Medicine
Dr. Richard Krasuski is Director of the Adult Congenital Heart Center at Duke University Medical Center, the Director of Hemodynamic Research, and the Medical Director of the CTEPH Program. He is considered a thought leader in the fields of pulmonary hypertension and congenital heart disease. His research focus is in epidemiologic and clinical studies involving patients with pulmonary hypertension and patients with congenital heart disease. He is involved in multiple multicenter studies thr
Patel

Priyesh Patel

Assistant Professor of Medicine
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