Heart Transplantation and Mechanical Circulatory Support in Adults with Congenital Heart Disease.
Abstract
PURPOSE OF REVIEW:To assess current management strategies for advanced heart failure
in adults with congenital heart disease, including heart transplantation and mechanical
circulatory support. RECENT FINDINGS:Current data demonstrate that adults with CHD
generally experience higher short-term mortality after heart transplantation and MCS
implantation, but enjoy superior long-term survival. Such patients are nonetheless
less likely to receive a transplant than non-ACHD peers due to a variety of factors,
including lack of applicability of current listing criteria to HF in ACHD. MCS is
underutilized in ACHD, but provides similar quality of life benefits for ACHD and
non-ACHD patients alike. Heart failure in ACHD is complex and difficult to treat,
and both heart transplantation and mechanical circulatory support are often challenging
to implement in this patient population. However, long-term results are encouraging,
and existing data supports increasing use of MCS and transplant earlier in their disease
course. Multidisciplinary care is critical to success in these complex patients.
Type
Journal articleSubject
Adult congenital heart diseaseFailing Fontan
Heart transplantation
LVAD
Mechanical circulatory support
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https://hdl.handle.net/10161/17940Published Version (Please cite this version)
10.1007/s11886-018-1028-1Publication Info
Serfas, John D; Patel, Priyesh A; & Krasuski, Richard A (2018). Heart Transplantation and Mechanical Circulatory Support in Adults with Congenital
Heart Disease. Current cardiology reports, 20(10). pp. 81. 10.1007/s11886-018-1028-1. Retrieved from https://hdl.handle.net/10161/17940.This is constructed from limited available data and may be imprecise. To cite this
article, please review & use the official citation provided by the journal.
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Show full item recordScholars@Duke
Richard Andrew Krasuski
Professor of Medicine
Dr. Richard Krasuski is Director of the Adult Congenital Heart Center at Duke University
Medical Center, the Director of Hemodynamic Research, and the Medical Director of
the CTEPH Program. He is considered a thought leader in the fields of pulmonary hypertension
and congenital heart disease. His research focus is in epidemiologic and clinical
studies involving patients with pulmonary hypertension and patients with congenital
heart disease. He is involved in multiple multicenter studies thr
Priyesh Patel
Assistant Professor of Medicine
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