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Pulmonary Delivery of Therapeutic and Diagnostic Gases.

dc.contributor.author Charles, Hal
dc.contributor.author MacIntyre, Neil
dc.contributor.author Mammarappallil, Joseph
dc.contributor.author Moon, Richard
dc.contributor.author Zapol, Warren M
dc.contributor.author Martin, Andrew R
dc.contributor.author Sá, Rui C
dc.contributor.author Yu, Binglan
dc.contributor.author Ichinose, Fumito
dc.contributor.author Chen, John Z
dc.contributor.author Geier, Eric T
dc.contributor.author Darquenne, Chantal
dc.contributor.author Prisk, G Kim
dc.contributor.author Katz, Ira
dc.date.accessioned 2019-03-01T14:44:05Z
dc.date.available 2019-03-01T14:44:05Z
dc.date.issued 2018-04
dc.identifier.issn 1941-2711
dc.identifier.issn 1941-2703
dc.identifier.uri https://hdl.handle.net/10161/18102
dc.description.abstract The 21st Congress for the International Society for Aerosols in Medicine included, for the first time, a session on Pulmonary Delivery of Therapeutic and Diagnostic Gases. The rationale for such a session within ISAM is that the pulmonary delivery of gaseous drugs in many cases targets the same therapeutic areas as aerosol drug delivery, and is in many scientific and technical aspects similar to aerosol drug delivery. This article serves as a report on the recent ISAM congress session providing a synopsis of each of the presentations. The topics covered are the conception, testing, and development of the use of nitric oxide to treat pulmonary hypertension; the use of realistic adult nasal replicas to evaluate the performance of pulsed oxygen delivery devices; an overview of several diagnostic gas modalities; and the use of inhaled oxygen as a proton magnetic resonance imaging (MRI) contrast agent for imaging temporal changes in the distribution of specific ventilation during recovery from bronchoconstriction. Themes common to these diverse applications of inhaled gases in medicine are discussed, along with future perspectives on development of therapeutic and diagnostic gases.
dc.language eng
dc.publisher Mary Ann Liebert Inc
dc.relation.ispartof Journal of aerosol medicine and pulmonary drug delivery
dc.relation.isversionof 10.1089/jamp.2017.1431
dc.subject in vitro upper airway model
dc.subject lung imaging
dc.subject magnetic resonance imaging (MRI)
dc.subject nitric oxide
dc.subject oxygen
dc.subject pulmonary hypertension
dc.title Pulmonary Delivery of Therapeutic and Diagnostic Gases.
dc.type Journal article
dc.date.updated 2019-03-01T14:44:04Z
pubs.begin-page 78
pubs.end-page 87
pubs.issue 2
pubs.organisational-group School of Medicine
pubs.organisational-group Duke
pubs.organisational-group Radiology, Cardiothoracic Imaging
pubs.organisational-group Radiology
pubs.organisational-group Clinical Science Departments
pubs.organisational-group Medicine, Pulmonary, Allergy, and Critical Care Medicine
pubs.organisational-group Medicine
pubs.organisational-group Anesthesiology, General, Vascular, High Risk Transplant & Critical Care
pubs.organisational-group Anesthesiology
pubs.organisational-group Duke Cancer Institute
pubs.organisational-group Institutes and Centers
pubs.publication-status Published
pubs.volume 31


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